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- W2023651332 abstract "This report describes the natural history, clinical features, and therapeutic requirements of late-onset seropositive and/or erosive rheumatoid arthritis (LORA). One hundred twenty-nine patients with mean disease duration of 6 years and mean age of disease onset of 66 years were studied. All patients met American Rheumatism Association criteria for rheumatoid arthritis (RA). Ninety-one percent were seropositive for rheumatoid factor, 83% had erosive disease, and 58% had significant medical problems. Therapeutically, most patients required sequential use of multiple second-line agents. Functional classification did not change significantly despite treatment, and complete remissions were unusual even with remittive therapy. It is concluded that a subset of LORA patients have seropositive aggressive, destructive disease." @default.
- W2023651332 created "2016-06-24" @default.
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- W2023651332 date "1993-12-01" @default.
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- W2023651332 title "Late-onset, seropositive, erosive rheumatoid arthritis" @default.
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- W2023651332 doi "https://doi.org/10.1016/s0049-0172(05)80038-1" @default.
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