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• W2023652879 endingPage "162" @default.
• W2023652879 startingPage "150" @default.
• W2023652879 abstract "The melanocortin system consists of melanocortin peptides derived from the proopiomelanocortin gene (in particular adrenocorticotropic hormone, ACTH, and melanocyte-stimulating hormones, MSH) and five melanocortin receptor subtypes (MC1R-MC5R). Knowledge of the melanocortin system in fish is still limited, but information on the receptor part of the system is very rapidly growing. The melanocortin receptors (MCRs) have been recently cloned from several species of fish. The amino acid sequences appear remarkably well conserved. Pharmacological characterisation studies of the first identified piscine MCRs indicate that ACTH may be the original ligand for the MCRs, while the MSH peptides gained specialised functions in the course of evolution. Considering the tissue distribution of the MCRs, there are two distinctions between mammals and fish: where in mammals the MC4R is exclusively expressed in the central nervous system, in the fish species examined so far it is also peripherally expressed. It does however, alike the situation in mammals, likely play a key role in the central regulation of food intake and energy balance. Not only the MCRs, but also many other factors involved herewith, have been found in fish and roughly appear to function similarly as in mammals. The second difference is the distribution of the MC5R, which appears less widely expressed in fish than in mammals. Considering the available data it is predicted that, in mammals and fish alike, skin colouration is mediated via MC1R and steroidogenesis via MC2R. This review provides a short overview of the basic molecular characteristics, pharmacology, and tissue distribution of the MCRs in the fish investigated up to now, as well as their physiological role in the processes of skin colouration, steroidogenesis, and feeding behaviour." @default.
• W2023652879 created "2016-06-24" @default.
• W2023652879 creator A5005293502 @default.
• W2023652879 creator A5024467624 @default.
• W2023652879 creator A5080801101 @default.
• W2023652879 date "2006-09-01" @default.
• W2023652879 modified "2023-10-03" @default.
• W2023652879 title "Molecular biology and physiology of the melanocortin system in fish: A review" @default.
• W2023652879 cites W1485475012 @default.
• W2023652879 cites W1488596761 @default.
• W2023652879 cites W1503357410 @default.
• W2023652879 cites W1557479171 @default.
• W2023652879 cites W1563417707 @default.
• W2023652879 cites W1566308385 @default.
• W2023652879 cites W1779019576 @default.
• W2023652879 cites W1964488668 @default.
• W2023652879 cites W1967863599 @default.
• W2023652879 cites W1973772334 @default.
• W2023652879 cites W1975404084 @default.
• W2023652879 cites W1975631118 @default.
• W2023652879 cites W1975697197 @default.
• W2023652879 cites W1975952809 @default.
• W2023652879 cites W1977582104 @default.
• W2023652879 cites W1978709185 @default.
• W2023652879 cites W1979420492 @default.
• W2023652879 cites W1982527304 @default.
• W2023652879 cites W1982787384 @default.
• W2023652879 cites W1984011330 @default.
• W2023652879 cites W1987385863 @default.
• W2023652879 cites W1989030284 @default.
• W2023652879 cites W1989993782 @default.
• W2023652879 cites W1994197690 @default.
• W2023652879 cites W1997675153 @default.
• W2023652879 cites W1999452048 @default.
• W2023652879 cites W2000183149 @default.
• W2023652879 cites W2004429756 @default.
• W2023652879 cites W2005123729 @default.
• W2023652879 cites W2006399278 @default.
• W2023652879 cites W2006849207 @default.
• W2023652879 cites W2008162623 @default.
• W2023652879 cites W2008782354 @default.
• W2023652879 cites W2010142606 @default.
• W2023652879 cites W2012080968 @default.
• W2023652879 cites W2012180839 @default.
• W2023652879 cites W2015451996 @default.
• W2023652879 cites W2021106556 @default.
• W2023652879 cites W2021631954 @default.
• W2023652879 cites W2025017526 @default.
• W2023652879 cites W2025085604 @default.
• W2023652879 cites W2030138411 @default.
• W2023652879 cites W2035631285 @default.
• W2023652879 cites W2040563972 @default.
• W2023652879 cites W2041531639 @default.
• W2023652879 cites W2042658226 @default.
• W2023652879 cites W2050442066 @default.
• W2023652879 cites W2051988666 @default.
• W2023652879 cites W2057959883 @default.
• W2023652879 cites W2061240699 @default.
• W2023652879 cites W2063763885 @default.
• W2023652879 cites W2065389660 @default.
• W2023652879 cites W2065569912 @default.
• W2023652879 cites W2065833650 @default.
• W2023652879 cites W2067328017 @default.
• W2023652879 cites W2068519421 @default.
• W2023652879 cites W2075182826 @default.
• W2023652879 cites W2079497611 @default.
• W2023652879 cites W2082341809 @default.
• W2023652879 cites W2083116048 @default.
• W2023652879 cites W2083338331 @default.
• W2023652879 cites W2084547258 @default.
• W2023652879 cites W2084677170 @default.
• W2023652879 cites W2086722805 @default.
• W2023652879 cites W2090460315 @default.
• W2023652879 cites W2094185207 @default.
• W2023652879 cites W2095253225 @default.
• W2023652879 cites W2105429765 @default.
• W2023652879 cites W2105470099 @default.
• W2023652879 cites W2106099541 @default.
• W2023652879 cites W2116479366 @default.
• W2023652879 cites W2119101110 @default.
• W2023652879 cites W2120635941 @default.
• W2023652879 cites W2129873761 @default.
• W2023652879 cites W2133418139 @default.
• W2023652879 cites W2136061619 @default.
• W2023652879 cites W2136226486 @default.
• W2023652879 cites W2137845412 @default.
• W2023652879 cites W2328234674 @default.
• W2023652879 cites W4237331024 @default.
• W2023652879 cites W4238499560 @default.
• W2023652879 cites W4243673086 @default.
• W2023652879 cites W4244409070 @default.
• W2023652879 cites W4253396467 @default.
• W2023652879 doi "https://doi.org/10.1016/j.ygcen.2006.03.001" @default.
• W2023652879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16620815" @default.
• W2023652879 hasPublicationYear "2006" @default.
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