Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023653650> ?p ?o ?g. }
- W2023653650 endingPage "22" @default.
- W2023653650 startingPage "15" @default.
- W2023653650 abstract "G protein coupled receptors and tropomyosin‐related kinase (Trk) receptors have distinct structure and transducing mechanisms; therefore, cross‐talk among them was unexpected. Evidence has, however, accumulated showing that tonic adenosine A2A receptor activity is a required step to allow synaptic actions of neurotrophic factors, namely upon synaptic transmission at both pre‐ and post‐synaptic level as well as upon synaptic plasticity. An enhancement of A2A receptor tonus upon ageing may partially compensate the loss of TrkB receptors, rescuing to certain degree the facilitatory action of brain derived neurotrophic factor in aged animals, which might prove particularly relevant in the prevention of neurodegeneration upon ageing. A2A receptors also trigger synaptic actions of other neurotrophic factors, such as glial derived neurotrophic factor at dopaminergic striatal nerve endings. The growing evidence that tonic adenosine A2A receptor activity is a crucial step to allow actions of neurotrophic factors in neurones will be reviewed and discussed in the light of therapeutic strategies for neurodegenerative diseases." @default.
- W2023653650 created "2016-06-24" @default.
- W2023653650 creator A5021255614 @default.
- W2023653650 creator A5031806410 @default.
- W2023653650 date "2009-08-25" @default.
- W2023653650 modified "2023-09-25" @default.
- W2023653650 title "Triggering neurotrophic factor actions through adenosine A2A receptor activation: implications for neuroprotection" @default.
- W2023653650 cites W1530428799 @default.
- W2023653650 cites W1551550807 @default.
- W2023653650 cites W1552552113 @default.
- W2023653650 cites W1571586310 @default.
- W2023653650 cites W1579287598 @default.
- W2023653650 cites W1601854110 @default.
- W2023653650 cites W1603988625 @default.
- W2023653650 cites W1915062990 @default.
- W2023653650 cites W1969088709 @default.
- W2023653650 cites W1969515810 @default.
- W2023653650 cites W1972137168 @default.
- W2023653650 cites W1973860833 @default.
- W2023653650 cites W1973998682 @default.
- W2023653650 cites W1976656679 @default.
- W2023653650 cites W1976681153 @default.
- W2023653650 cites W1976874229 @default.
- W2023653650 cites W1979103691 @default.
- W2023653650 cites W1980965097 @default.
- W2023653650 cites W1989034907 @default.
- W2023653650 cites W1989944353 @default.
- W2023653650 cites W1990362631 @default.
- W2023653650 cites W1990479642 @default.
- W2023653650 cites W1991323513 @default.
- W2023653650 cites W1991987289 @default.
- W2023653650 cites W1993374742 @default.
- W2023653650 cites W1993636230 @default.
- W2023653650 cites W1995387616 @default.
- W2023653650 cites W2001110103 @default.
- W2023653650 cites W2002613500 @default.
- W2023653650 cites W2003338841 @default.
- W2023653650 cites W2006682240 @default.
- W2023653650 cites W2009868913 @default.
- W2023653650 cites W2010114986 @default.
- W2023653650 cites W2010121960 @default.
- W2023653650 cites W2015117347 @default.
- W2023653650 cites W2017547114 @default.
- W2023653650 cites W2017900230 @default.
- W2023653650 cites W2018885303 @default.
- W2023653650 cites W2020268088 @default.
- W2023653650 cites W2024860017 @default.
- W2023653650 cites W2029565457 @default.
- W2023653650 cites W2030125834 @default.
- W2023653650 cites W2030549077 @default.
- W2023653650 cites W2031964878 @default.
- W2023653650 cites W2033442386 @default.
- W2023653650 cites W2034380892 @default.
- W2023653650 cites W2037721754 @default.
- W2023653650 cites W2042272714 @default.
- W2023653650 cites W2044350453 @default.
- W2023653650 cites W2045540976 @default.
- W2023653650 cites W2045678127 @default.
- W2023653650 cites W2054755464 @default.
- W2023653650 cites W2058026578 @default.
- W2023653650 cites W2060411448 @default.
- W2023653650 cites W2061473590 @default.
- W2023653650 cites W2062214351 @default.
- W2023653650 cites W2063849763 @default.
- W2023653650 cites W2065098417 @default.
- W2023653650 cites W2071776514 @default.
- W2023653650 cites W2073642047 @default.
- W2023653650 cites W2075530232 @default.
- W2023653650 cites W2075621586 @default.
- W2023653650 cites W2077535383 @default.
- W2023653650 cites W2077720722 @default.
- W2023653650 cites W2078168701 @default.
- W2023653650 cites W2081486880 @default.
- W2023653650 cites W2083467935 @default.
- W2023653650 cites W2086108981 @default.
- W2023653650 cites W2086528223 @default.
- W2023653650 cites W2088862264 @default.
- W2023653650 cites W2094690399 @default.
- W2023653650 cites W2094778727 @default.
- W2023653650 cites W2095099413 @default.
- W2023653650 cites W2120168553 @default.
- W2023653650 cites W2128960139 @default.
- W2023653650 cites W2141150594 @default.
- W2023653650 cites W2146267270 @default.
- W2023653650 cites W2156202012 @default.
- W2023653650 cites W2157714782 @default.
- W2023653650 cites W2162772229 @default.
- W2023653650 cites W2163639252 @default.
- W2023653650 doi "https://doi.org/10.1111/j.1476-5381.2009.00157.x" @default.
- W2023653650 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2795259" @default.
- W2023653650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19508402" @default.
- W2023653650 hasPublicationYear "2009" @default.
- W2023653650 type Work @default.
- W2023653650 sameAs 2023653650 @default.
- W2023653650 citedByCount "61" @default.
- W2023653650 countsByYear W20236536502012 @default.
- W2023653650 countsByYear W20236536502013 @default.
- W2023653650 countsByYear W20236536502014 @default.