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- W2023654436 abstract "A series of new 2-(2-aminopyrimidin-4-yl)phenol derivatives were synthesized as potential antitumor compounds. Substitution with pyrrolidine-3,4-diol at the 4-position of phenol provided potent inhibitory activity against CDK1 and CDK2. X-ray crystal structural studies were performed to account for the effect of the substituent on both the enzymatic and cell growth inhibitory activities." @default.
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- W2023654436 date "2011-07-01" @default.
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- W2023654436 title "Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors" @default.
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- W2023654436 doi "https://doi.org/10.1016/j.bmcl.2011.05.081" @default.
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