FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023661688> ?p ?o ?g. }

• W2023661688 endingPage "1660" @default.
• W2023661688 startingPage "1650" @default.
• W2023661688 abstract "Data derived from gene expression microarrays often are used for purposes of classification and discovery. Many methods have been proposed for accomplishing these and related aims, however the statistical properties of such methods generally are not well established. To this end, it is desirable to develop realistic mathematical and statistical models that can be used in a simulation context so that the impacts of data analysis methods and testing approaches can be established. A method is developed in which variation among arrays can be characterized simultaneously for a large number of genes resulting in a multivariate model of gene expression. The method is based on selecting mathematical transformations of the underlying expression measures such that the transformed variables follow approximately a Gaussian distribution, and then estimating associated parameters, including correlations. The result is a multivariate normal distribution that serves to model transformed gene expression values within a subject population, while accounting for covariances among genes and/or probes. This model then is used to simulate microarray expression and probe intensity data by employing a modified Cholesky matrix factorization technique which addresses the singularity problem for the “small n, big p” situation. An example is given using prostate cancer data and, as an illustration, it is shown how data normalization can be investigated using this approach." @default.
• W2023661688 created "2016-06-24" @default.
• W2023661688 creator A5055154856 @default.
• W2023661688 creator A5071433358 @default.
• W2023661688 creator A5080658074 @default.
• W2023661688 date "2009-03-01" @default.
• W2023661688 modified "2023-10-17" @default.
• W2023661688 title "Distribution modeling and simulation of gene expression data" @default.
• W2023661688 cites W1877206895 @default.
• W2023661688 cites W2010015275 @default.
• W2023661688 cites W2036796028 @default.
• W2023661688 cites W2037458463 @default.
• W2023661688 cites W2052566161 @default.
• W2023661688 cites W2053627399 @default.
• W2023661688 cites W2073644113 @default.
• W2023661688 cites W2079963825 @default.
• W2023661688 cites W2087982523 @default.
• W2023661688 cites W2105981176 @default.
• W2023661688 cites W2118759687 @default.
• W2023661688 cites W2126226510 @default.
• W2023661688 cites W2130530904 @default.
• W2023661688 cites W2131070718 @default.
• W2023661688 cites W2131680275 @default.
• W2023661688 cites W2134338931 @default.
• W2023661688 cites W2135437145 @default.
• W2023661688 cites W2159400887 @default.
• W2023661688 cites W2170989872 @default.
• W2023661688 cites W2336392079 @default.
• W2023661688 cites W4242046871 @default.
• W2023661688 cites W4249966633 @default.
• W2023661688 doi "https://doi.org/10.1016/j.csda.2008.03.023" @default.
• W2023661688 hasPublicationYear "2009" @default.
• W2023661688 type Work @default.
• W2023661688 sameAs 2023661688 @default.
• W2023661688 citedByCount "25" @default.
• W2023661688 countsByYear W20236616882012 @default.
• W2023661688 countsByYear W20236616882013 @default.
• W2023661688 countsByYear W20236616882014 @default.
• W2023661688 countsByYear W20236616882015 @default.
• W2023661688 countsByYear W20236616882017 @default.
• W2023661688 countsByYear W20236616882018 @default.
• W2023661688 countsByYear W20236616882019 @default.
• W2023661688 countsByYear W20236616882020 @default.
• W2023661688 crossrefType "journal-article" @default.
• W2023661688 hasAuthorship W2023661688A5055154856 @default.
• W2023661688 hasAuthorship W2023661688A5071433358 @default.
• W2023661688 hasAuthorship W2023661688A5080658074 @default.
• W2023661688 hasConcept C11413529 @default.
• W2023661688 hasConcept C119857082 @default.
• W2023661688 hasConcept C121332964 @default.
• W2023661688 hasConcept C124101348 @default.
• W2023661688 hasConcept C136886441 @default.
• W2023661688 hasConcept C144024400 @default.
• W2023661688 hasConcept C149923435 @default.
• W2023661688 hasConcept C158693339 @default.
• W2023661688 hasConcept C161584116 @default.
• W2023661688 hasConcept C163716315 @default.
• W2023661688 hasConcept C177384507 @default.
• W2023661688 hasConcept C19165224 @default.
• W2023661688 hasConcept C199360897 @default.
• W2023661688 hasConcept C2908647359 @default.
• W2023661688 hasConcept C33923547 @default.
• W2023661688 hasConcept C34727166 @default.
• W2023661688 hasConcept C41008148 @default.
• W2023661688 hasConcept C62520636 @default.
• W2023661688 hasConcept C90559484 @default.
• W2023661688 hasConceptScore W2023661688C11413529 @default.
• W2023661688 hasConceptScore W2023661688C119857082 @default.
• W2023661688 hasConceptScore W2023661688C121332964 @default.
• W2023661688 hasConceptScore W2023661688C124101348 @default.
• W2023661688 hasConceptScore W2023661688C136886441 @default.
• W2023661688 hasConceptScore W2023661688C144024400 @default.
• W2023661688 hasConceptScore W2023661688C149923435 @default.
• W2023661688 hasConceptScore W2023661688C158693339 @default.
• W2023661688 hasConceptScore W2023661688C161584116 @default.
• W2023661688 hasConceptScore W2023661688C163716315 @default.
• W2023661688 hasConceptScore W2023661688C177384507 @default.
• W2023661688 hasConceptScore W2023661688C19165224 @default.
• W2023661688 hasConceptScore W2023661688C199360897 @default.
• W2023661688 hasConceptScore W2023661688C2908647359 @default.
• W2023661688 hasConceptScore W2023661688C33923547 @default.
• W2023661688 hasConceptScore W2023661688C34727166 @default.
• W2023661688 hasConceptScore W2023661688C41008148 @default.
• W2023661688 hasConceptScore W2023661688C62520636 @default.
• W2023661688 hasConceptScore W2023661688C90559484 @default.
• W2023661688 hasIssue "5" @default.
• W2023661688 hasLocation W20236616881 @default.
• W2023661688 hasOpenAccess W2023661688 @default.
• W2023661688 hasPrimaryLocation W20236616881 @default.
• W2023661688 hasRelatedWork W1530312010 @default.
• W2023661688 hasRelatedWork W2015240834 @default.
• W2023661688 hasRelatedWork W2047059769 @default.
• W2023661688 hasRelatedWork W2086688912 @default.
• W2023661688 hasRelatedWork W2091300140 @default.
• W2023661688 hasRelatedWork W22179779 @default.
• W2023661688 hasRelatedWork W2790402973 @default.
• W2023661688 hasRelatedWork W2963872526 @default.
• W2023661688 hasRelatedWork W3123111387 @default.

• next