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- W2023671623 abstract "To examine the relationship between estrogen replacement therapy (ERT) and frontotemporal dementia (FTD).We examined the files of thirty female patients diagnosed with FTD at the University of California, San Francisco (UCSF)-Alzheimer's Disease Research Center in Fresno between the years of 1994 and 1999. Twenty-one patients (70%) were found to have been taking ERT at the time of their evaluation. This was compared with an estimate of estrogen use in a similar cohort from the general population (24%).Chi-square (chi(2)) analysis found this number to be significantly greater than estimates from the general population significant (chi(2)[df=1, N=30]=34.803, P<0.01).Three potential explanations for the findings are put forth, including an intriguing neurobiological relationship between estradiol and tau, the complex protein implicated in the etiology of FTD." @default.
- W2023671623 created "2016-06-24" @default.
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- W2023671623 date "2003-06-01" @default.
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- W2023671623 title "Estrogen replacement therapy and frontotemporal dementia" @default.
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- W2023671623 doi "https://doi.org/10.1016/s0378-5122(03)00142-7" @default.
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