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- W2023676044 abstract "An 80-year-old woman was admitted for evaluation of a moderate thrombocytopenia. The patient had been asymptomatic until four days previously, when she had developed ecchymoses on both arms and the abdomen. On examination, there were large subcutaneous haemorrhages in a venepuncture area and in the abdomen there was a pulsatile abdominal mass. Laboratory results were: haemoglobin 12·7 g/dl, mean corpuscular volume 88·2 fl, white cell count 5·84 × 109/l, differential count and morphology normal, and platelet count 36 × 109/l, with normal morphology. Coagulation screening test results were partial thromboplastin time 41 s (control < 39 s), prothrombin time 16·3 s, fibrinogen 0·9 g/l and d dimer 293 μg/l (normal < 192 μg/l). A computerized tomography scan of the abdomen (performed with intravenous but not oral contrast medium) showed an abdominal aortic aneurysm more than 8 cm in diameter, with a very large mural thrombus (see images). A diagnosis of localized consumptive coagulopathy was made. The patient's status precluded aneurysmectomy. Localized consumption of platelets and fibrinogen may occur within an aortic aneurysm, and can produce both laboratory abnormalities and symptomatic bleeding. Treatment depends on surgical resection. The benefit of treatment with heparin or plasma is uncertain but is indicated in patients without an aneurysmal leak before surgical repair." @default.
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- W2023676044 date "2003-02-01" @default.
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- W2023676044 title "Thrombocytopenia and abdominal mass" @default.
- W2023676044 doi "https://doi.org/10.1046/j.1365-2141.2003.04031.x" @default.
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