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- W2023676869 abstract "A case of T‐cell chronic lymphocytic leukaemia is described. Intracerebellar tumour was demonstrated by the characteristic feature of contrast‐enhanced computerized tomography and was evidenced by surgical procedure. Histological examination revealed lymphocyte infiltration in the cerebellum. Initially, the majority of leukaemic cells were mature, medium‐sized lymphocytes with surface marker phenotype of E+, OKT3+, OKT4+, OKT6−, OKT8−. In the terminal stage, large atypical lymphocytes which were morphologically distinct from the original lymphocytes and had different surface marker phenotype of E+, OKT3+, OKT4−, OKT6−, OKT8+, Leu7+ became increasingly prominent. The remaining medium‐sized lymphocytes were morphologically and immunologically unchanged. Subsequently, the disease developed to a more aggressive pattern and the patient died in spite of chemotherapy." @default.
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- W2023676869 date "1986-05-01" @default.
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- W2023676869 title "Morphological and immunological change in the predominant type of leukaemic cells in a patient with T-cell chronic lymphocytic leukaemia" @default.
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- W2023676869 doi "https://doi.org/10.1111/j.1600-0609.1986.tb02278.x" @default.
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