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- W2023677939 abstract "Background and objective Two methods for measuring insulin sensitivity, fasting plasma insulin (FPI) and homeostasis model assessment (HOMA) have been proposed for use in large epidemiological research and clinical practice. This project describes the range of observed values of the HOMA and FPI in a large sample of the U.S. population. Methods We used fasting plasma glucose and insulin values from the Third National Health and Nutrition Survey (NHANES III) to identify the FPI and HOMA values. For both FPI and HOMA, higher values indicate lower insulin sensitivity. Results Among 6,511 participants without treated diabetes mellitus, FPI ranged from 1.8 to 175.8 μU/mL, with 25th percentile = 6.7, median = 9.3, 75th percentile = 13.3, and mean±1 SD = 11.2±7.5; HOMA ranged from 0.3 to 52.6 (mmol)(μU)/L2, with 25th percentile = 1.5, median = 2.2, 75th percentile = 3.3, and mean±SD = 2.8±2.4. Conclusion These findings describe the spectrum of insulin sensitivity and may be useful in helping physicians develop a clinical understanding of the dynamic range of both FPI and HOMA measures." @default.
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- W2023677939 date "2004-11-01" @default.
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- W2023677939 title "Two measures of insulin sensitivity provided similar information in a U.S. population" @default.
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- W2023677939 doi "https://doi.org/10.1016/j.jclinepi.2004.05.001" @default.
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