Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023680287> ?p ?o ?g. }
- W2023680287 endingPage "467" @default.
- W2023680287 startingPage "456" @default.
- W2023680287 abstract "Autophagy is a catabolic recycling pathway triggered by various intra- or extracellular stimuli that is conserved from yeast to mammals. During autophagy, diverse cytosolic constituents are enveloped by double-membrane vesicles, autophagosomes, which later fuse with lysosomes or the vacuole to degrade their cargo. Dysregulation in autophagy is associated with a diverse range of pathologies including cardiovascular disease, the leading cause of death in the world. Accordingly, there is tremendous interest in modulating autophagy for therapeutic purposes. One complexity with regard to cardiovascular homeostasis, however, is that the timing of autophagic activity appears to be critical; for example, cardiomyocyte autophagy during ischemia/reperfusion can be either beneficial or harmful. Here, we review the molecular mechanisms that govern autophagosome formation and analyze the link between autophagy and cardiovascular disease." @default.
- W2023680287 created "2016-06-24" @default.
- W2023680287 creator A5022277890 @default.
- W2023680287 creator A5037402761 @default.
- W2023680287 creator A5066515392 @default.
- W2023680287 creator A5080357903 @default.
- W2023680287 date "2015-01-30" @default.
- W2023680287 modified "2023-09-30" @default.
- W2023680287 title "Molecular Mechanisms of Autophagy in the Cardiovascular System" @default.
- W2023680287 cites W1523693806 @default.
- W2023680287 cites W1526993239 @default.
- W2023680287 cites W1555054913 @default.
- W2023680287 cites W1563735171 @default.
- W2023680287 cites W1754519657 @default.
- W2023680287 cites W1918384196 @default.
- W2023680287 cites W1964052965 @default.
- W2023680287 cites W1964257510 @default.
- W2023680287 cites W1964338913 @default.
- W2023680287 cites W1965827991 @default.
- W2023680287 cites W1967085696 @default.
- W2023680287 cites W1970637701 @default.
- W2023680287 cites W1972336737 @default.
- W2023680287 cites W1973472942 @default.
- W2023680287 cites W1974132613 @default.
- W2023680287 cites W1976720204 @default.
- W2023680287 cites W1976761774 @default.
- W2023680287 cites W1977767269 @default.
- W2023680287 cites W1978397479 @default.
- W2023680287 cites W1979228758 @default.
- W2023680287 cites W1980192302 @default.
- W2023680287 cites W1980942517 @default.
- W2023680287 cites W1981358316 @default.
- W2023680287 cites W1983831622 @default.
- W2023680287 cites W1986911872 @default.
- W2023680287 cites W1987240861 @default.
- W2023680287 cites W1989212506 @default.
- W2023680287 cites W1990247684 @default.
- W2023680287 cites W1993902882 @default.
- W2023680287 cites W1994239968 @default.
- W2023680287 cites W1994772532 @default.
- W2023680287 cites W1994817218 @default.
- W2023680287 cites W1996068251 @default.
- W2023680287 cites W1996427463 @default.
- W2023680287 cites W1999211990 @default.
- W2023680287 cites W1999259221 @default.
- W2023680287 cites W1999811798 @default.
- W2023680287 cites W2001467419 @default.
- W2023680287 cites W2001568034 @default.
- W2023680287 cites W2001676880 @default.
- W2023680287 cites W2003079927 @default.
- W2023680287 cites W2006544096 @default.
- W2023680287 cites W2008379702 @default.
- W2023680287 cites W2008417639 @default.
- W2023680287 cites W2012451546 @default.
- W2023680287 cites W2014205131 @default.
- W2023680287 cites W2014506057 @default.
- W2023680287 cites W2017828774 @default.
- W2023680287 cites W2018559323 @default.
- W2023680287 cites W2018652887 @default.
- W2023680287 cites W2018963148 @default.
- W2023680287 cites W2021919397 @default.
- W2023680287 cites W2022570265 @default.
- W2023680287 cites W2024600213 @default.
- W2023680287 cites W2025109763 @default.
- W2023680287 cites W2025205297 @default.
- W2023680287 cites W2026210863 @default.
- W2023680287 cites W2027082110 @default.
- W2023680287 cites W2030287946 @default.
- W2023680287 cites W2032186831 @default.
- W2023680287 cites W2036485081 @default.
- W2023680287 cites W2036568535 @default.
- W2023680287 cites W2036901614 @default.
- W2023680287 cites W2036903182 @default.
- W2023680287 cites W2039579794 @default.
- W2023680287 cites W2040157483 @default.
- W2023680287 cites W2040482760 @default.
- W2023680287 cites W2050224139 @default.
- W2023680287 cites W2056137479 @default.
- W2023680287 cites W2056663185 @default.
- W2023680287 cites W2060309271 @default.
- W2023680287 cites W2060438440 @default.
- W2023680287 cites W2062526619 @default.
- W2023680287 cites W2063650770 @default.
- W2023680287 cites W2064381459 @default.
- W2023680287 cites W2064729720 @default.
- W2023680287 cites W2065031087 @default.
- W2023680287 cites W2065126270 @default.
- W2023680287 cites W2066030465 @default.
- W2023680287 cites W2066733248 @default.
- W2023680287 cites W2068153705 @default.
- W2023680287 cites W2069938223 @default.
- W2023680287 cites W2070736092 @default.
- W2023680287 cites W2072544389 @default.
- W2023680287 cites W2073909046 @default.
- W2023680287 cites W2073963703 @default.
- W2023680287 cites W2073965098 @default.
- W2023680287 cites W2076381897 @default.
- W2023680287 cites W2076570319 @default.