Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023682312> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2023682312 endingPage "86" @default.
- W2023682312 startingPage "81" @default.
- W2023682312 abstract "The Spo11 protein is an eukaryotic homologue of the topoisomerase 6 subunit A from archaebacteria. In yeast Spo11p has been found to bind covalently to double-strand breaks (DSBs) during meiosis. Single homologues of the SPO11 gene exist in various eukaryotes, except plants. Previously, we found in the Arabidopsis thaliana genome two ancient paralogs, AtSPO11-1 and 2. Here we report on the molecular characterization of a third one, AtSPO11-3. This puzzling finding might be explained by the fact that we detected additionally – for the first time outside of the archaebacterial kingdom – a homologue of the subunit B of topoisomerase 6, AtTOP6B. Both AtSPO11-3 and AtTOP6B are abundantly expressed in Arabidopsis and EST comparisons indicate the presence of both genes in various plant species. Via two hybrid studies we could demonstrate that full length AtTop6B is able to interact with AtSpo11-2 and 3 but not with AtSpo11-1. Our data suggest that plants possess in contrast to other eukaryotes an additional archaebacterial kind of topoisomerase." @default.
- W2023682312 created "2016-06-24" @default.
- W2023682312 creator A5061846813 @default.
- W2023682312 creator A5070313247 @default.
- W2023682312 date "2001-06-01" @default.
- W2023682312 modified "2023-10-03" @default.
- W2023682312 title "Molecular characterization of homologues of both subunits A (SPO11) and B of the archaebacterial topoisomerase 6 in plants" @default.
- W2023682312 cites W1969575610 @default.
- W2023682312 cites W1974365473 @default.
- W2023682312 cites W2002454928 @default.
- W2023682312 cites W2011867412 @default.
- W2023682312 cites W2016505307 @default.
- W2023682312 cites W2023488322 @default.
- W2023682312 cites W2037623448 @default.
- W2023682312 cites W2040120176 @default.
- W2023682312 cites W2055043387 @default.
- W2023682312 cites W2078470736 @default.
- W2023682312 cites W2096193904 @default.
- W2023682312 cites W2098891503 @default.
- W2023682312 cites W2108871842 @default.
- W2023682312 cites W2109494124 @default.
- W2023682312 cites W2116280551 @default.
- W2023682312 cites W2118117928 @default.
- W2023682312 cites W2123374199 @default.
- W2023682312 cites W2142332997 @default.
- W2023682312 cites W2144550200 @default.
- W2023682312 cites W2164417370 @default.
- W2023682312 cites W2169185139 @default.
- W2023682312 doi "https://doi.org/10.1016/s0378-1119(01)00496-6" @default.
- W2023682312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11410368" @default.
- W2023682312 hasPublicationYear "2001" @default.
- W2023682312 type Work @default.
- W2023682312 sameAs 2023682312 @default.
- W2023682312 citedByCount "105" @default.
- W2023682312 countsByYear W20236823122012 @default.
- W2023682312 countsByYear W20236823122013 @default.
- W2023682312 countsByYear W20236823122014 @default.
- W2023682312 countsByYear W20236823122015 @default.
- W2023682312 countsByYear W20236823122016 @default.
- W2023682312 countsByYear W20236823122017 @default.
- W2023682312 countsByYear W20236823122018 @default.
- W2023682312 countsByYear W20236823122019 @default.
- W2023682312 countsByYear W20236823122020 @default.
- W2023682312 countsByYear W20236823122021 @default.
- W2023682312 countsByYear W20236823122022 @default.
- W2023682312 countsByYear W20236823122023 @default.
- W2023682312 crossrefType "journal-article" @default.
- W2023682312 hasAuthorship W2023682312A5061846813 @default.
- W2023682312 hasAuthorship W2023682312A5070313247 @default.
- W2023682312 hasConcept C104292427 @default.
- W2023682312 hasConcept C104317684 @default.
- W2023682312 hasConcept C141231307 @default.
- W2023682312 hasConcept C143065580 @default.
- W2023682312 hasConcept C147897179 @default.
- W2023682312 hasConcept C2775988993 @default.
- W2023682312 hasConcept C2777576037 @default.
- W2023682312 hasConcept C2779491563 @default.
- W2023682312 hasConcept C54355233 @default.
- W2023682312 hasConcept C552990157 @default.
- W2023682312 hasConcept C86803240 @default.
- W2023682312 hasConceptScore W2023682312C104292427 @default.
- W2023682312 hasConceptScore W2023682312C104317684 @default.
- W2023682312 hasConceptScore W2023682312C141231307 @default.
- W2023682312 hasConceptScore W2023682312C143065580 @default.
- W2023682312 hasConceptScore W2023682312C147897179 @default.
- W2023682312 hasConceptScore W2023682312C2775988993 @default.
- W2023682312 hasConceptScore W2023682312C2777576037 @default.
- W2023682312 hasConceptScore W2023682312C2779491563 @default.
- W2023682312 hasConceptScore W2023682312C54355233 @default.
- W2023682312 hasConceptScore W2023682312C552990157 @default.
- W2023682312 hasConceptScore W2023682312C86803240 @default.
- W2023682312 hasIssue "1" @default.
- W2023682312 hasLocation W20236823121 @default.
- W2023682312 hasLocation W20236823122 @default.
- W2023682312 hasOpenAccess W2023682312 @default.
- W2023682312 hasPrimaryLocation W20236823121 @default.
- W2023682312 hasRelatedWork W1521187372 @default.
- W2023682312 hasRelatedWork W2030501883 @default.
- W2023682312 hasRelatedWork W2071720405 @default.
- W2023682312 hasRelatedWork W2114217399 @default.
- W2023682312 hasRelatedWork W2123065529 @default.
- W2023682312 hasRelatedWork W2136320374 @default.
- W2023682312 hasRelatedWork W2139902187 @default.
- W2023682312 hasRelatedWork W2310564984 @default.
- W2023682312 hasRelatedWork W2947569759 @default.
- W2023682312 hasRelatedWork W4285140261 @default.
- W2023682312 hasVolume "271" @default.
- W2023682312 isParatext "false" @default.
- W2023682312 isRetracted "false" @default.
- W2023682312 magId "2023682312" @default.
- W2023682312 workType "article" @default.