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- W2023684147 abstract "In rhesus monkeys acclimated to primate restraining chairs, cannulae were implanted bilaterally in the lateral cerebral ventricles. Solutions of ethanol (8 or 12%), acetaldehyde (0.1 %) or paraldehyde (0.1 %) were infused chronically in a volume of 0.1 ml every 15 min around the clock. Each animal was offered a choice of water or a solution of ethanol which was increased in concentration from 3–30% over an 11–13 day sequence. The results showed that in three of four monkeys, the chronic infusion of ethanol evoked sudden and intermittent increases in ethanol intake which varied in terms of onset of preference as well as concentrations preferred. The other two substances had no reliable effect on preference except that in two of three monkeys, acetaldehyde infused intraventricularly evoked an increase in ethanol intake after the chronic infusions had been terminated. These findings indicate that the phenomenon of abnormal ethanol-preference induced by intracerebral ethanol is not species-specific." @default.
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- W2023684147 date "1972-03-01" @default.
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- W2023684147 title "Preference for ethanol in the rhesus monkey following chronic infusion of ethanol into the cerebral ventricles" @default.
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- W2023684147 doi "https://doi.org/10.1016/0031-9384(72)90324-1" @default.
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