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- W2023688537 abstract "Abstract The kinetics of a generalized monovalent carrier and some polyvalent carriers have been investigated both in the absence and presence of an electrical field. It is shown that polyvalent carriers might give rise to a variety of kinetic characteristics and may resemble under certain conditions monovalent carriers. At low concentration of substrate the flux ratio should equal the electrochemical activity ratio raised to a power equal to the valency of the carrier but at high concentration deviation towards exchange diffusion may occur. The results are discussed in relation to glucose transport in the red cell and in relation to the detection of exchange diffusion by removing substrate from the outer compartment. The relative merits of a long pore and a polyvalent carrier are compared in connection with K + permeability in squid axon; and it is suggested that the transient changes of K + permeability might be due to a redistribution of an electrical field acting on a polyvalent carrier. The possibility that such a redistribution of electrical field might also account for Na + permeability in the axon is also briefly investigated." @default.
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- W2023688537 date "1966-01-01" @default.
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- W2023688537 title "Fluxes in passive, monovalent and polyvalent carrier systems" @default.
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- W2023688537 doi "https://doi.org/10.1016/0022-5193(66)90177-9" @default.
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