Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023689336> ?p ?o ?g. }
- W2023689336 endingPage "1260" @default.
- W2023689336 startingPage "1252" @default.
- W2023689336 abstract "Noninvasive imaging of the brain of animal models demands the detection of increasingly smaller structures by in vivo MRI. The purpose of this work was to elucidate the spatial resolution and structural contrast that can be obtained for studying the brain of C57BL/6J mice by optimized T2-weighted fast spin-echo MRI at 9.4 T. As a prerequisite for high-resolution imaging in vivo, motion artifacts were abolished by combining volatile anesthetics and positive pressure ventilation with a specially designed animal bed for fixation. Multiple substructures in the cortex, olfactory bulb, hippocampus, and cerebellum were resolved at 30 to 40 μm in-plane resolution and 200 to 300 μm section thickness as well as for relatively long echo times of 65 to 82 ms. In particular, the approach resulted in the differentiation of up to five cortical layers. In the olfactory bulb the images unraveled the mitral cell layer which has a thickness of mostly single cells. In the hippocampus at least five substructures could be separated. The molecular layer, Purkinje layer, and granular layer of the cerebellum could be clearly differentiated from the white matter. In conclusion, even without the use of a contrast agent, suitable adjustments of a widely available T2-weighted MRI sequence at high field allow for structural MRI of living mice at near single-cell layer resolution." @default.
- W2023689336 created "2016-06-24" @default.
- W2023689336 creator A5011406899 @default.
- W2023689336 creator A5062629404 @default.
- W2023689336 creator A5070456854 @default.
- W2023689336 creator A5078016491 @default.
- W2023689336 creator A5082870988 @default.
- W2023689336 date "2009-10-01" @default.
- W2023689336 modified "2023-10-15" @default.
- W2023689336 title "MRI of cellular layers in mouse brain in vivo" @default.
- W2023689336 cites W1920079548 @default.
- W2023689336 cites W1963624472 @default.
- W2023689336 cites W1978921440 @default.
- W2023689336 cites W1989484896 @default.
- W2023689336 cites W1997732141 @default.
- W2023689336 cites W1999450284 @default.
- W2023689336 cites W2021791787 @default.
- W2023689336 cites W2024410850 @default.
- W2023689336 cites W2050305501 @default.
- W2023689336 cites W2053466687 @default.
- W2023689336 cites W2055844985 @default.
- W2023689336 cites W2058108897 @default.
- W2023689336 cites W2058291001 @default.
- W2023689336 cites W2061919826 @default.
- W2023689336 cites W2068863154 @default.
- W2023689336 cites W2069981080 @default.
- W2023689336 cites W2071074898 @default.
- W2023689336 cites W2073093756 @default.
- W2023689336 cites W2085764202 @default.
- W2023689336 cites W2086031793 @default.
- W2023689336 cites W2087021951 @default.
- W2023689336 cites W2087328731 @default.
- W2023689336 cites W2088665704 @default.
- W2023689336 cites W2093834083 @default.
- W2023689336 cites W2099642308 @default.
- W2023689336 cites W2106919606 @default.
- W2023689336 cites W2111692402 @default.
- W2023689336 cites W2115070053 @default.
- W2023689336 cites W2118161962 @default.
- W2023689336 cites W2129347928 @default.
- W2023689336 cites W2130452967 @default.
- W2023689336 cites W2130749199 @default.
- W2023689336 cites W2154878091 @default.
- W2023689336 cites W2165298588 @default.
- W2023689336 doi "https://doi.org/10.1016/j.neuroimage.2009.05.095" @default.
- W2023689336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19520174" @default.
- W2023689336 hasPublicationYear "2009" @default.
- W2023689336 type Work @default.
- W2023689336 sameAs 2023689336 @default.
- W2023689336 citedByCount "53" @default.
- W2023689336 countsByYear W20236893362012 @default.
- W2023689336 countsByYear W20236893362013 @default.
- W2023689336 countsByYear W20236893362014 @default.
- W2023689336 countsByYear W20236893362015 @default.
- W2023689336 countsByYear W20236893362016 @default.
- W2023689336 countsByYear W20236893362017 @default.
- W2023689336 countsByYear W20236893362018 @default.
- W2023689336 countsByYear W20236893362019 @default.
- W2023689336 countsByYear W20236893362020 @default.
- W2023689336 countsByYear W20236893362021 @default.
- W2023689336 countsByYear W20236893362022 @default.
- W2023689336 countsByYear W20236893362023 @default.
- W2023689336 crossrefType "journal-article" @default.
- W2023689336 hasAuthorship W2023689336A5011406899 @default.
- W2023689336 hasAuthorship W2023689336A5062629404 @default.
- W2023689336 hasAuthorship W2023689336A5070456854 @default.
- W2023689336 hasAuthorship W2023689336A5078016491 @default.
- W2023689336 hasAuthorship W2023689336A5082870988 @default.
- W2023689336 hasConcept C104317684 @default.
- W2023689336 hasConcept C121332964 @default.
- W2023689336 hasConcept C126838900 @default.
- W2023689336 hasConcept C136229726 @default.
- W2023689336 hasConcept C143409427 @default.
- W2023689336 hasConcept C146249460 @default.
- W2023689336 hasConcept C150903083 @default.
- W2023689336 hasConcept C169760540 @default.
- W2023689336 hasConcept C185592680 @default.
- W2023689336 hasConcept C207001950 @default.
- W2023689336 hasConcept C2778472085 @default.
- W2023689336 hasConcept C2779652256 @default.
- W2023689336 hasConcept C2780496858 @default.
- W2023689336 hasConcept C2780680797 @default.
- W2023689336 hasConcept C2781161787 @default.
- W2023689336 hasConcept C2781192897 @default.
- W2023689336 hasConcept C46141821 @default.
- W2023689336 hasConcept C529278444 @default.
- W2023689336 hasConcept C55493867 @default.
- W2023689336 hasConcept C71924100 @default.
- W2023689336 hasConcept C86803240 @default.
- W2023689336 hasConceptScore W2023689336C104317684 @default.
- W2023689336 hasConceptScore W2023689336C121332964 @default.
- W2023689336 hasConceptScore W2023689336C126838900 @default.
- W2023689336 hasConceptScore W2023689336C136229726 @default.
- W2023689336 hasConceptScore W2023689336C143409427 @default.
- W2023689336 hasConceptScore W2023689336C146249460 @default.
- W2023689336 hasConceptScore W2023689336C150903083 @default.
- W2023689336 hasConceptScore W2023689336C169760540 @default.
- W2023689336 hasConceptScore W2023689336C185592680 @default.