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• W2023689781 abstract "Dermatophagoides farinae Hughes, American house dust mite, is highly allergenic, producing symptoms in people worldwide. Identifying and cloning the allergens in this species may enable better diagnostic and therapeutic approaches. Here, we cloned, sequenced, and expressed the full-length cDNA encoding D. farinae group 10 allergen (Der f 10) isolated from dust mites in China. Bioinformatic analysis indicated that the 888 bp sequence encoded a cytoskeleton protein 295 amino acids long, with a molecular weight of approximately equal 34 kDa. Sequence alignment with the group 10 allergens of Pyroglyphidae, Acaridae, and Glycyphagidae families revealed that the group 10 allergen from D. farinae is 95% similar to D. pteronyssinus Trouessart and Psoroptes ovis (Hering). These findings lay the groundwork for future studies, including large-scale production of recombinant Der f 10 allergen for diagnostic and therapeutic agents." @default.
• W2023689781 created "2016-06-24" @default.
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• W2023689781 date "2013-01-01" @default.
• W2023689781 modified "2023-09-25" @default.
• W2023689781 title "The Group 10 Allergen of<i>Dermatophagoides farinae</i>(Acari: Pyroglyphidae): cDNA Cloning, Sequence Analysis, and Expression in<i>Escherichia coli</i>BL21" @default.
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• W2023689781 doi "https://doi.org/10.1603/me12019" @default.
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