FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023694018> ?p ?o ?g. }

• W2023694018 endingPage "025005" @default.
• W2023694018 startingPage "025005" @default.
• W2023694018 abstract "Fabrication of customized implants based on patient bone defect characteristics is required for successful clinical application of bone tissue engineering. Recently a new surgical procedure, tibial tuberosity advancement (TTA), has been used to treat cranial cruciate ligament (CrCL) deficient stifle joints in dogs, which involves an osteotomy and the use of substitutes to restore the bone. However, limitations in the use of non-biodegradable implants have been reported. To overcome these limitations, this study presents the development of a bioceramic customized cage to treat a large domestic dog assigned for TTA treatment. A cage was designed using a suitable topology optimization methodology in order to maximize its permeability whilst maintaining the structural integrity, and was manufactured using low temperature 3D printing and implanted in a dog. The cage material and structure was adequately characterized prior to implantation and the in vivo response was carefully monitored regarding the biological response and patient limb function. The manufacturing process resulted in a cage composed of brushite, monetite and tricalcium phosphate, and a highly permeable porous morphology. An overall porosity of 59.2% was achieved by the combination of a microporosity of approximately 40% and a designed interconnected macropore network with pore sizes of 845 μm. The mechanical properties were in the range of the trabecular bone although limitations in the cage's reliability and capacity to absorb energy were identified. The dog's limb function was completely restored without patient lameness or any adverse complications and also the local biocompatibility and osteoconductivity were improved. Based on these observations it was possible to conclude that the successful design, fabrication and application of a customized cage for a dog CrCL treatment using a modified TTA technique is a promising method for the future fabrication of patient-specific bone implants, although clinical trials are required." @default.
• W2023694018 created "2016-06-24" @default.
• W2023694018 creator A5001603091 @default.
• W2023694018 creator A5023305082 @default.
• W2023694018 creator A5030326061 @default.
• W2023694018 creator A5032244976 @default.
• W2023694018 creator A5042625954 @default.
• W2023694018 creator A5060948870 @default.
• W2023694018 creator A5069343339 @default.
• W2023694018 creator A5071274944 @default.
• W2023694018 creator A5087359417 @default.
• W2023694018 creator A5090921422 @default.
• W2023694018 date "2014-03-21" @default.
• W2023694018 modified "2023-10-01" @default.
• W2023694018 title "Application of a 3D printed customized implant for canine cruciate ligament treatment by tibial tuberosity advancement" @default.
• W2023694018 cites W1860674949 @default.
• W2023694018 cites W1913198287 @default.
• W2023694018 cites W1916868462 @default.
• W2023694018 cites W1966805140 @default.
• W2023694018 cites W1967696528 @default.
• W2023694018 cites W1969811096 @default.
• W2023694018 cites W1970305837 @default.
• W2023694018 cites W1971339046 @default.
• W2023694018 cites W1972878337 @default.
• W2023694018 cites W1976500358 @default.
• W2023694018 cites W1989581196 @default.
• W2023694018 cites W1994625357 @default.
• W2023694018 cites W1996857750 @default.
• W2023694018 cites W1999215151 @default.
• W2023694018 cites W2000621835 @default.
• W2023694018 cites W2001380203 @default.
• W2023694018 cites W2013056443 @default.
• W2023694018 cites W2015689456 @default.
• W2023694018 cites W2018145050 @default.
• W2023694018 cites W2019836836 @default.
• W2023694018 cites W2022692623 @default.
• W2023694018 cites W2026975571 @default.
• W2023694018 cites W2027578917 @default.
• W2023694018 cites W2030977129 @default.
• W2023694018 cites W2035399778 @default.
• W2023694018 cites W2035408362 @default.
• W2023694018 cites W2035596893 @default.
• W2023694018 cites W2038581418 @default.
• W2023694018 cites W2039237521 @default.
• W2023694018 cites W2040753795 @default.
• W2023694018 cites W2041558541 @default.
• W2023694018 cites W2042581802 @default.
• W2023694018 cites W2047719890 @default.
• W2023694018 cites W2050677453 @default.
• W2023694018 cites W2053048548 @default.
• W2023694018 cites W2057599193 @default.
• W2023694018 cites W2063825036 @default.
• W2023694018 cites W2064705140 @default.
• W2023694018 cites W2065739747 @default.
• W2023694018 cites W2067045707 @default.
• W2023694018 cites W2071436788 @default.
• W2023694018 cites W2075651517 @default.
• W2023694018 cites W2078024098 @default.
• W2023694018 cites W2079904737 @default.
• W2023694018 cites W2083804071 @default.
• W2023694018 cites W2086762695 @default.
• W2023694018 cites W2090763065 @default.
• W2023694018 cites W2094603740 @default.
• W2023694018 cites W2109520485 @default.
• W2023694018 cites W2109656249 @default.
• W2023694018 cites W2110803235 @default.
• W2023694018 cites W2113854599 @default.
• W2023694018 cites W2114050481 @default.
• W2023694018 cites W2117315764 @default.
• W2023694018 cites W2122951429 @default.
• W2023694018 cites W2128403970 @default.
• W2023694018 cites W2130934825 @default.
• W2023694018 cites W2136691001 @default.
• W2023694018 cites W2152082639 @default.
• W2023694018 cites W2159222922 @default.
• W2023694018 cites W2166168951 @default.
• W2023694018 cites W2187544091 @default.
• W2023694018 cites W2223796212 @default.
• W2023694018 cites W2467205692 @default.
• W2023694018 cites W2506800878 @default.
• W2023694018 cites W2727420541 @default.
• W2023694018 cites W4205490020 @default.
• W2023694018 cites W4296792842 @default.
• W2023694018 doi "https://doi.org/10.1088/1758-5082/6/2/025005" @default.
• W2023694018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24658159" @default.
• W2023694018 hasPublicationYear "2014" @default.
• W2023694018 type Work @default.
• W2023694018 sameAs 2023694018 @default.
• W2023694018 citedByCount "55" @default.
• W2023694018 countsByYear W20236940182015 @default.
• W2023694018 countsByYear W20236940182016 @default.
• W2023694018 countsByYear W20236940182017 @default.
• W2023694018 countsByYear W20236940182018 @default.
• W2023694018 countsByYear W20236940182019 @default.
• W2023694018 countsByYear W20236940182020 @default.
• W2023694018 countsByYear W20236940182021 @default.
• W2023694018 countsByYear W20236940182022 @default.
• W2023694018 countsByYear W20236940182023 @default.

• next