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- W2023696392 abstract "The effect of the coagulant fraction from Agkistrodon rhodostoma venom (ancrod) on the generation of glomerular microclots was studied in rabbits. Infusions of ancrod, aprotinin and norepinephrine caused formation of glomerular microclots in a high percentage, whereas infusion of ancrod and aprotinin or ancrod and norepinephrine resulted in microclots only in few rabbits. The formation of microclots could not be prevented by treating the animals with heparin, but heparin increased the percentage of animals exhibiting fibrin-like material in the glomerular capillaries after infusions of ancrod, aprotinin and norepinephrine. The results suggest that circulating ancrod-induced soluble fibrin is precipitated, thus forming microclots in connection with platelets. The process of precipitation is independent of the coagulation system, but represents one step in microclot formation in disseminated intravascular coagulation." @default.
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- W2023696392 date "1973-04-01" @default.
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- W2023696392 title "Precipitation of ancrod-induced soluble fibrin by aprotinin and norepinephrine" @default.
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