FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023696968> ?p ?o ?g. }

• W2023696968 endingPage "S37" @default.
• W2023696968 startingPage "S33" @default.
• W2023696968 abstract "Autophagy, an evolutionary highly conserved process in virtually all eukaryotic cells, involves the sequestration of cytosol regions within double-membrane bound compartments and delivery of the contents to the lysosomes for degradation. Rapidly accumulating evidence has shown that autophagy is a component of innate immunity and is involved in host defense elimination of pathogens. Our previous studies show that Toll-like receptor 4 (TLR4) is a sensor for autophagy associated with innate immunity. We, now, further demonstrate that LPS or poly(I:C)-treatment significantly reduced mycobacterial viability in mouse macrophages. In addition, LPS reduction of mycobacterial viability was abrogated with the use of autophagy inhibitor 3-MA and in autophagy deficient macrophages. These findings demonstrate that TLR3 or TLR4 stimulation induces autophagy-mediated elimination of mycobacteria in macrophages. These results provide groundwork for therapeutic strategies directed at elimination of mycobacterial infections in macrophages." @default.
• W2023696968 created "2016-06-24" @default.
• W2023696968 creator A5010912348 @default.
• W2023696968 creator A5015016762 @default.
• W2023696968 creator A5040799018 @default.
• W2023696968 creator A5041087708 @default.
• W2023696968 creator A5052564248 @default.
• W2023696968 date "2013-12-01" @default.
• W2023696968 modified "2023-10-18" @default.
• W2023696968 title "Harnessing of TLR-mediated autophagy to combat mycobacteria in macrophages" @default.
• W2023696968 cites W1550722396 @default.
• W2023696968 cites W1973314755 @default.
• W2023696968 cites W1978751572 @default.
• W2023696968 cites W1988327539 @default.
• W2023696968 cites W1992245975 @default.
• W2023696968 cites W2012451546 @default.
• W2023696968 cites W2016040396 @default.
• W2023696968 cites W2034172998 @default.
• W2023696968 cites W2042260827 @default.
• W2023696968 cites W2117063200 @default.
• W2023696968 cites W2157778451 @default.
• W2023696968 cites W2160131728 @default.
• W2023696968 cites W2792139654 @default.
• W2023696968 doi "https://doi.org/10.1016/s1472-9792(13)70008-8" @default.
• W2023696968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24388647" @default.
• W2023696968 hasPublicationYear "2013" @default.
• W2023696968 type Work @default.
• W2023696968 sameAs 2023696968 @default.
• W2023696968 citedByCount "24" @default.
• W2023696968 countsByYear W20236969682013 @default.
• W2023696968 countsByYear W20236969682014 @default.
• W2023696968 countsByYear W20236969682015 @default.
• W2023696968 countsByYear W20236969682016 @default.
• W2023696968 countsByYear W20236969682017 @default.
• W2023696968 countsByYear W20236969682018 @default.
• W2023696968 countsByYear W20236969682019 @default.
• W2023696968 countsByYear W20236969682020 @default.
• W2023696968 countsByYear W20236969682021 @default.
• W2023696968 crossrefType "journal-article" @default.
• W2023696968 hasAuthorship W2023696968A5010912348 @default.
• W2023696968 hasAuthorship W2023696968A5015016762 @default.
• W2023696968 hasAuthorship W2023696968A5040799018 @default.
• W2023696968 hasAuthorship W2023696968A5041087708 @default.
• W2023696968 hasAuthorship W2023696968A5052564248 @default.
• W2023696968 hasConcept C136449434 @default.
• W2023696968 hasConcept C160448771 @default.
• W2023696968 hasConcept C161478664 @default.
• W2023696968 hasConcept C170493617 @default.
• W2023696968 hasConcept C190283241 @default.
• W2023696968 hasConcept C202751555 @default.
• W2023696968 hasConcept C203014093 @default.
• W2023696968 hasConcept C203522944 @default.
• W2023696968 hasConcept C2776070231 @default.
• W2023696968 hasConcept C2776709828 @default.
• W2023696968 hasConcept C2778420691 @default.
• W2023696968 hasConcept C2779244956 @default.
• W2023696968 hasConcept C2779341262 @default.
• W2023696968 hasConcept C55493867 @default.
• W2023696968 hasConcept C62478195 @default.
• W2023696968 hasConcept C86803240 @default.
• W2023696968 hasConcept C8891405 @default.
• W2023696968 hasConcept C89423630 @default.
• W2023696968 hasConcept C95444343 @default.
• W2023696968 hasConceptScore W2023696968C136449434 @default.
• W2023696968 hasConceptScore W2023696968C160448771 @default.
• W2023696968 hasConceptScore W2023696968C161478664 @default.
• W2023696968 hasConceptScore W2023696968C170493617 @default.
• W2023696968 hasConceptScore W2023696968C190283241 @default.
• W2023696968 hasConceptScore W2023696968C202751555 @default.
• W2023696968 hasConceptScore W2023696968C203014093 @default.
• W2023696968 hasConceptScore W2023696968C203522944 @default.
• W2023696968 hasConceptScore W2023696968C2776070231 @default.
• W2023696968 hasConceptScore W2023696968C2776709828 @default.
• W2023696968 hasConceptScore W2023696968C2778420691 @default.
• W2023696968 hasConceptScore W2023696968C2779244956 @default.
• W2023696968 hasConceptScore W2023696968C2779341262 @default.
• W2023696968 hasConceptScore W2023696968C55493867 @default.
• W2023696968 hasConceptScore W2023696968C62478195 @default.
• W2023696968 hasConceptScore W2023696968C86803240 @default.
• W2023696968 hasConceptScore W2023696968C8891405 @default.
• W2023696968 hasConceptScore W2023696968C89423630 @default.
• W2023696968 hasConceptScore W2023696968C95444343 @default.
• W2023696968 hasLocation W20236969681 @default.
• W2023696968 hasLocation W20236969682 @default.
• W2023696968 hasOpenAccess W2023696968 @default.
• W2023696968 hasPrimaryLocation W20236969681 @default.
• W2023696968 hasRelatedWork W1988327539 @default.
• W2023696968 hasRelatedWork W1997630199 @default.
• W2023696968 hasRelatedWork W1998525621 @default.
• W2023696968 hasRelatedWork W2005312649 @default.
• W2023696968 hasRelatedWork W2023696968 @default.
• W2023696968 hasRelatedWork W2103339779 @default.
• W2023696968 hasRelatedWork W2145019698 @default.
• W2023696968 hasRelatedWork W2410240262 @default.
• W2023696968 hasRelatedWork W2588193271 @default.
• W2023696968 hasRelatedWork W2614703160 @default.
• W2023696968 hasVolume "93" @default.
• W2023696968 isParatext "false" @default.

• next