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- W2023699384 abstract "A cDNA for a member of the G protein-coupled receptor family was isolated from Drosophila using a probe derived from a human β2-adrenergic receptor cDNA. This Drosophila receptor gene is localized at 99A10-B1 on the right arm of chromosome 3 and is preferentially expressed in Drosophila heads. The insect octopamine receptor has been permanently expressed in mammalian cells, where it mediates the attenuation of adenylate cyclase activity and exhibits a pharmacological profile consistent with an octopamine type 1 receptor. Sequence and pharmacological comparisons indicate that the octopamine receptor is unique but closely related to mammalian adrenergic receptors, perhaps as an evolutionary precursor." @default.
- W2023699384 created "2016-06-24" @default.
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- W2023699384 date "1990-03-01" @default.
- W2023699384 modified "2023-10-16" @default.
- W2023699384 title "Cloning, localization, and permanent expression of a Drosophila octopamine receptor" @default.
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- W2023699384 doi "https://doi.org/10.1016/0896-6273(90)90047-j" @default.
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