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- W2023700250 abstract "La saturación periférica de oxígeno (SpO2) medida por oximetría de pulso es ampliamente usada en la práctica clínica, pero sus fluctuaciones durante las 24 h del día han sido poco exploradas. Recientemente describimos que niños hospitalizados por causas no cardiopulmonares tenían una variación circadiana de la SpO2. Este hallazgo necesitaba ser corroborado en niños sanos, lo que constituyó la finalidad del presente estudio. Niños sanos residentes en una casa cuna gubernamental se estudiaron mediante oximetría de pulso cada 2 h a lo largo de 24 h. Se incluyeron 82 niños de un mes a 6,5 años de edad (media ± error estándar: 3,06 ± 0,16 años), con peso para la talla en el percentil 65,5 ± 2,9. En 65 (79,3%) niños los valores de SpO2 siguieron una curva sinusoidal sugestiva de un ritmo circadiano. El conjunto de curvas sinusoidales en esta población tuvo un mesor de 95,10 ± 0,08%SpO2 y un período de 21,05 ± 0,54 h (en el 53,8% de estos niños el período estuvo entre 20 y 28 h). El valor máximo de SpO2 se alcanzó a las 3:14 PM ± 16 min, y el más bajo a las 5:16 AM ± 48 min. Al dividir las 24 h en 4 períodos se demostró que los valores más altos de SpO2 se alcanzaban entre las 2 PM y las 8 PM. En esta población de niños clínicamente sanos existió una variación circadiana en la oximetría de pulso, con valores máximos a media tarde y mínimos en la madrugada. Peripheral oxygen saturation (SpO2) measured by pulse oximetry is widely used in clinical practice, but its fluctuations over the course of the 24 h of a day have not been explored at length. Recently, we reported that children hospitalized due to non-cardiopulmonary causes had a circadian variation in SpO2. This finding needed to be corroborated in healthy children, which is the objective of the present study. Healthy children residing in a state foster home were studied with pulse oximetry every 2 h for 24 h. Eighty two children were included in the study, ranging in age from one month to 6.5 years (average ± standard error of 3.06 ± 0.16 years), with a weight-for-length/height percentile of 65.5 ± 2.9. In 65 (79.3%) children, the SpO2 levels followed a sinusoidal curve suggesting circadian rhythm. The total group of sinusoidal curves in this population had a mesor of 95.10 ± 0.08% SpO2, period of 21.05 ± 0.54 h (in 53.8% of these children, the period was between 20 and 28 h). The maximum SpO2 was reached at 3:14 PM ± 16 min, and the minimum at 5:16 AM ± 48 min. When the 24 h were divided into four periods, it was demonstrated that the highest SpO2 levels were reached between 2 PM and 8 PM. In this population of clinically healthy children, there was a circadian variation in pulse oximetry, with maximum values in the late afternoon and minimal values in the early morning." @default.
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- W2023700250 date "2012-06-01" @default.
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- W2023700250 title "Variabilidad circadiana de la oximetría de pulso en niños sanos menores de 7 años" @default.
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- W2023700250 doi "https://doi.org/10.1016/j.arbres.2012.02.004" @default.
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