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- W2023702854 abstract "Hypocretin/orexin deficiency appears to be a consistent feature of narcolepsy with a putative autoimmune mechanism involved. We treated four hypocretin/orexin-deficient narcolepsy patients with intravenous immunoglobulins and assessed the efficacy by repeated polysomnographies and questionnaires. Three patients received the treatment within a few months after acute onset of narcolepsy. A clear improvement in the frequency and severity of cataplexy was obtained with a benefic effect up to 7 months without any anticataplectics drugs at follow-up. Our findings point to the importance of early diagnosis of narcolepsy, which once treated quickly may modify its long-term outlook." @default.
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- W2023702854 date "2004-11-23" @default.
- W2023702854 modified "2023-10-10" @default.
- W2023702854 title "Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset" @default.
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- W2023702854 doi "https://doi.org/10.1002/ana.20339" @default.
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