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- W2023706685 endingPage "1691" @default.
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- W2023706685 abstract "Energy transfer provides an arrow in the metabolism of living systems. Direct energetic coupling of chemical transformations, such that the free energy generated in one reaction is channeled to another, is the essence of energy transfer, whereas the purpose is the production of high-energy chemical intermediates. Vitamin K provides a particularly instructive example of energy transfer. A key principle at work in the vitamin K system can be termed base strength amplification. In the base strength amplification sequence, the free energy of oxygenation of vitamin K hydroquinone (vitamin KH2) is used to transform a weak base to a strong base in order to effect proton removal from selected glutamate (Glu) residues in the blood-clotting proteins." @default.
- W2023706685 created "2016-06-24" @default.
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- W2023706685 date "1995-09-22" @default.
- W2023706685 modified "2023-09-26" @default.
- W2023706685 title "Vitamin K and Energy Transduction: A Base Strength Amplification Mechanism" @default.
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- W2023706685 doi "https://doi.org/10.1126/science.7569894" @default.
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