FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023707089> ?p ?o ?g. }

• W2023707089 endingPage "365" @default.
• W2023707089 startingPage "355" @default.
• W2023707089 abstract "Metabolic and hormonal effects of muscular exercise were studied in juvenile-type diabetics in relation to the prevailing degree of metabolic control and compared with those in healthy control subjects. Two groups of diabetic patients, one in moderate metabolic control and one in ketosis due to insulin withdrawal, were subjected to a 3 hour bicycle ergometer test of comparable, mild work intensity. In both groups of diabetics the exercise-induced rise in blood lactate was similar, but was significantly higher than in control subjects. Blood alanine levels showed a transient, significant rise in both diabetic groups, but not in controls. Blood concentrations of branch-chained amino acids remained unchanged. In the moderately controlled diabetics, exercise induced a marked fall of blood glucose and increases in blood levels of free fatty acids (FFA), ketone bodies and glucagon, which were comparable to the exercise effects in normal controls. In ketotic diabetics, however, exercise led to an additional rise in blood glucose concentration and to increases in ketone body, glucagon and cortisol levels. Significant correlations were found between the exercise effect on blood glucose and initial blood levels of glucose, FFA, ketone bodies and branch chained amino acids: pre-exercise values of above 325 mg/dl glucose, 1173 μmol/l FFA, 2.13 mmol/l ketone bodies and 0.74 mmol/l branch chained amino acids led to increased blood glucose levels on exercise, whereas below these limits glucose fell during the exercise test. These findings seem to be, at least in part, explained by the hypothesis of a permissive effect of insulin during stimulation of muscle glucose uptake by exercise. The increased circulating levels of glucagon and cortisol during exercise in ketotic diabetics might represent additional hyperglycaemic and, probably more important, lipolytic and ketogenic stimuli. The results suggest that in moderately controlled, non-ketotic diabetics blood glucose falls during exercise; in ketotic, relatively insulin deficient patients, muscular activity has adverse metabolic and hormonal effects: a further increase in blood glucose, plasma glucagon and cortisol and a rapid aggravation of ketosis." @default.
• W2023707089 created "2016-06-24" @default.
• W2023707089 creator A5003659724 @default.
• W2023707089 creator A5004738864 @default.
• W2023707089 creator A5025782216 @default.
• W2023707089 creator A5026333520 @default.
• W2023707089 creator A5045186756 @default.
• W2023707089 creator A5048975617 @default.
• W2023707089 creator A5058841582 @default.
• W2023707089 creator A5063355352 @default.
• W2023707089 creator A5073102724 @default.
• W2023707089 creator A5079778863 @default.
• W2023707089 creator A5084246386 @default.
• W2023707089 date "1977-08-01" @default.
• W2023707089 modified "2023-10-15" @default.
• W2023707089 title "Metabolic and hormonal effects of muscular exercise in juvenile type diabetics" @default.
• W2023707089 cites W1594124800 @default.
• W2023707089 cites W1689213241 @default.
• W2023707089 cites W1700450537 @default.
• W2023707089 cites W1848227690 @default.
• W2023707089 cites W1890547526 @default.
• W2023707089 cites W1953942880 @default.
• W2023707089 cites W1967297611 @default.
• W2023707089 cites W1972145506 @default.
• W2023707089 cites W1984224264 @default.
• W2023707089 cites W1989888046 @default.
• W2023707089 cites W1990840796 @default.
• W2023707089 cites W1996652844 @default.
• W2023707089 cites W2002702306 @default.
• W2023707089 cites W2003781513 @default.
• W2023707089 cites W2010301061 @default.
• W2023707089 cites W2011527163 @default.
• W2023707089 cites W2031988539 @default.
• W2023707089 cites W2036885504 @default.
• W2023707089 cites W2037347288 @default.
• W2023707089 cites W2039346214 @default.
• W2023707089 cites W2042316825 @default.
• W2023707089 cites W2050273160 @default.
• W2023707089 cites W2058245088 @default.
• W2023707089 cites W2060511578 @default.
• W2023707089 cites W2069623087 @default.
• W2023707089 cites W2069824034 @default.
• W2023707089 cites W2082598345 @default.
• W2023707089 cites W2091980720 @default.
• W2023707089 cites W2092818400 @default.
• W2023707089 cites W2105777288 @default.
• W2023707089 cites W2111327129 @default.
• W2023707089 cites W2135191741 @default.
• W2023707089 cites W2135268895 @default.
• W2023707089 cites W2136112043 @default.
• W2023707089 cites W2146415791 @default.
• W2023707089 cites W2146533011 @default.
• W2023707089 cites W2146975459 @default.
• W2023707089 cites W2161680978 @default.
• W2023707089 cites W2165426876 @default.
• W2023707089 cites W2336349166 @default.
• W2023707089 cites W2402984141 @default.
• W2023707089 cites W2405559133 @default.
• W2023707089 cites W2408263220 @default.
• W2023707089 cites W2443129672 @default.
• W2023707089 cites W2473626178 @default.
• W2023707089 cites W2575459552 @default.
• W2023707089 cites W93517807 @default.
• W2023707089 doi "https://doi.org/10.1007/bf01223279" @default.
• W2023707089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/410693" @default.
• W2023707089 hasPublicationYear "1977" @default.
• W2023707089 type Work @default.
• W2023707089 sameAs 2023707089 @default.
• W2023707089 citedByCount "234" @default.
• W2023707089 countsByYear W20237070892012 @default.
• W2023707089 countsByYear W20237070892013 @default.
• W2023707089 countsByYear W20237070892014 @default.
• W2023707089 countsByYear W20237070892015 @default.
• W2023707089 countsByYear W20237070892016 @default.
• W2023707089 countsByYear W20237070892017 @default.
• W2023707089 countsByYear W20237070892018 @default.
• W2023707089 countsByYear W20237070892019 @default.
• W2023707089 countsByYear W20237070892020 @default.
• W2023707089 countsByYear W20237070892021 @default.
• W2023707089 countsByYear W20237070892022 @default.
• W2023707089 crossrefType "journal-article" @default.
• W2023707089 hasAuthorship W2023707089A5003659724 @default.
• W2023707089 hasAuthorship W2023707089A5004738864 @default.
• W2023707089 hasAuthorship W2023707089A5025782216 @default.
• W2023707089 hasAuthorship W2023707089A5026333520 @default.
• W2023707089 hasAuthorship W2023707089A5045186756 @default.
• W2023707089 hasAuthorship W2023707089A5048975617 @default.
• W2023707089 hasAuthorship W2023707089A5058841582 @default.
• W2023707089 hasAuthorship W2023707089A5063355352 @default.
• W2023707089 hasAuthorship W2023707089A5073102724 @default.
• W2023707089 hasAuthorship W2023707089A5079778863 @default.
• W2023707089 hasAuthorship W2023707089A5084246386 @default.
• W2023707089 hasBestOaLocation W20237070891 @default.
• W2023707089 hasConcept C126322002 @default.
• W2023707089 hasConcept C134018914 @default.
• W2023707089 hasConcept C181588539 @default.
• W2023707089 hasConcept C185592680 @default.
• W2023707089 hasConcept C2776731943 @default.

• next