FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023708839> ?p ?o ?g. }

• W2023708839 endingPage "24" @default.
• W2023708839 startingPage "19" @default.
• W2023708839 abstract "Oxidative stress plays a role in the pathogenesis of neurodegeneration in diabetic retinopathy (DR). However, whether an excellent reactive oxygen species scavenger, U83836E, inhibits the neurodegeneration in DR remains uncertain. This study is aimed at clarifying the effects of U83836E on DR. Two weeks after streptozotocin (STZ) injection, diabetic rats and control animals were assigned at random to receive U83836E or vehicle for 2 weeks. Transmission electron microscopy and electroretinography were used to observe the changes in retina ultrastructure and electrophysiological function, respectively; superoxide dismutase (SOD) activity and malondialdehyde (MDA) levels were measured using a spectrometer. STZ-induced diabetic rats showed obvious vacuolation and many swollen mitochondria in the retinal ganglion cells of the retina, and reduced amplitudes of b-waves and oscillatory potentials. Concomitantly, there was a decrease in SOD activity and increase in MDA levels. These changes were inhibited by U83836E. These results suggest that U83836E improves neurodegeneration in DR and possesses a great potential for the treatment of DR." @default.
• W2023708839 created "2016-06-24" @default.
• W2023708839 creator A5012391493 @default.
• W2023708839 creator A5033020983 @default.
• W2023708839 creator A5034073274 @default.
• W2023708839 creator A5036112465 @default.
• W2023708839 creator A5084138424 @default.
• W2023708839 date "2010-11-27" @default.
• W2023708839 modified "2023-10-16" @default.
• W2023708839 title "U83836E Inhibits Retinal Neurodegeneration in Early-Stage Streptozotocin-Induced Diabetic Rats" @default.
• W2023708839 cites W127872553 @default.
• W2023708839 cites W1968161608 @default.
• W2023708839 cites W1970781885 @default.
• W2023708839 cites W1972317764 @default.
• W2023708839 cites W1978896256 @default.
• W2023708839 cites W1980131509 @default.
• W2023708839 cites W1985681315 @default.
• W2023708839 cites W1999146990 @default.
• W2023708839 cites W2016846438 @default.
• W2023708839 cites W2029860978 @default.
• W2023708839 cites W2055940918 @default.
• W2023708839 cites W2068686903 @default.
• W2023708839 cites W2071581482 @default.
• W2023708839 cites W2074453873 @default.
• W2023708839 cites W2090484837 @default.
• W2023708839 cites W2112015480 @default.
• W2023708839 cites W21187677 @default.
• W2023708839 cites W2122178701 @default.
• W2023708839 cites W2125806058 @default.
• W2023708839 cites W2126711468 @default.
• W2023708839 cites W2142693924 @default.
• W2023708839 cites W2160397772 @default.
• W2023708839 cites W2162837978 @default.
• W2023708839 cites W2171994468 @default.
• W2023708839 doi "https://doi.org/10.1159/000321952" @default.
• W2023708839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21109760" @default.
• W2023708839 hasPublicationYear "2010" @default.
• W2023708839 type Work @default.
• W2023708839 sameAs 2023708839 @default.
• W2023708839 citedByCount "10" @default.
• W2023708839 countsByYear W20237088392013 @default.
• W2023708839 countsByYear W20237088392015 @default.
• W2023708839 countsByYear W20237088392016 @default.
• W2023708839 countsByYear W20237088392017 @default.
• W2023708839 countsByYear W20237088392018 @default.
• W2023708839 countsByYear W20237088392020 @default.
• W2023708839 countsByYear W20237088392021 @default.
• W2023708839 countsByYear W20237088392022 @default.
• W2023708839 crossrefType "journal-article" @default.
• W2023708839 hasAuthorship W2023708839A5012391493 @default.
• W2023708839 hasAuthorship W2023708839A5033020983 @default.
• W2023708839 hasAuthorship W2023708839A5034073274 @default.
• W2023708839 hasAuthorship W2023708839A5036112465 @default.
• W2023708839 hasAuthorship W2023708839A5084138424 @default.
• W2023708839 hasConcept C126322002 @default.
• W2023708839 hasConcept C134018914 @default.
• W2023708839 hasConcept C169760540 @default.
• W2023708839 hasConcept C185592680 @default.
• W2023708839 hasConcept C2775838275 @default.
• W2023708839 hasConcept C2776151105 @default.
• W2023708839 hasConcept C2776925932 @default.
• W2023708839 hasConcept C2777093970 @default.
• W2023708839 hasConcept C2778401633 @default.
• W2023708839 hasConcept C2779113765 @default.
• W2023708839 hasConcept C2779134260 @default.
• W2023708839 hasConcept C2779280383 @default.
• W2023708839 hasConcept C2779829184 @default.
• W2023708839 hasConcept C2780827179 @default.
• W2023708839 hasConcept C48349386 @default.
• W2023708839 hasConcept C55493867 @default.
• W2023708839 hasConcept C555293320 @default.
• W2023708839 hasConcept C71924100 @default.
• W2023708839 hasConcept C86803240 @default.
• W2023708839 hasConceptScore W2023708839C126322002 @default.
• W2023708839 hasConceptScore W2023708839C134018914 @default.
• W2023708839 hasConceptScore W2023708839C169760540 @default.
• W2023708839 hasConceptScore W2023708839C185592680 @default.
• W2023708839 hasConceptScore W2023708839C2775838275 @default.
• W2023708839 hasConceptScore W2023708839C2776151105 @default.
• W2023708839 hasConceptScore W2023708839C2776925932 @default.
• W2023708839 hasConceptScore W2023708839C2777093970 @default.
• W2023708839 hasConceptScore W2023708839C2778401633 @default.
• W2023708839 hasConceptScore W2023708839C2779113765 @default.
• W2023708839 hasConceptScore W2023708839C2779134260 @default.
• W2023708839 hasConceptScore W2023708839C2779280383 @default.
• W2023708839 hasConceptScore W2023708839C2779829184 @default.
• W2023708839 hasConceptScore W2023708839C2780827179 @default.
• W2023708839 hasConceptScore W2023708839C48349386 @default.
• W2023708839 hasConceptScore W2023708839C55493867 @default.
• W2023708839 hasConceptScore W2023708839C555293320 @default.
• W2023708839 hasConceptScore W2023708839C71924100 @default.
• W2023708839 hasConceptScore W2023708839C86803240 @default.
• W2023708839 hasIssue "1" @default.
• W2023708839 hasLocation W20237088391 @default.
• W2023708839 hasLocation W20237088392 @default.
• W2023708839 hasOpenAccess W2023708839 @default.
• W2023708839 hasPrimaryLocation W20237088391 @default.
• W2023708839 hasRelatedWork W1995071802 @default.

• next