FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023708977> ?p ?o ?g. }

• W2023708977 endingPage "4534" @default.
• W2023708977 startingPage "4530" @default.
• W2023708977 abstract "The surface proteins of lymphocytes from spleen and thymus and several cultured lymphoid tumor lines were radioiodinated in situ, solubilized with Triton X-100, and examined for the presence of disulfide-bonded subunits by two-dimensional (intact, reduced) NaDodSO4/polyacrylamide gel electrophoresis. [Hynes, R. O. & Destree, A. (1977) Proc. Natl. Acad. Sci. USA 74, 2855-2859]. Few lymphocyte surface proteins were found to consist of disulfide-bonded subunits, and the most prominent of these could be identified. In normal B lymphocytes and B-lymphoma cells, IgD or IgM (or both) were the major disulfide-bonded proteins, and these were easily detectable, even without immunoprecipitation. In contrast, analysis of thymocytes and T-lymphoma cells did not reveal any protein resembling immunoglobulin in its chain structure. The major labeled thymocyte membrane protein consisting of disulfide-bonded subunits was identified as the Ly-2/3 antigen. It appeared to contain disulfide-bonded homodimers of Mr 35,000 (alpha 2) noncovalently associated with a second pair of homodimers of Mr 30,000 (beta 2). Peptide mapping showed these polypeptides to be homologous. A third disulfide-bonded homodimer, which was heterogeneous in apparent Mr, appeared to be part of the Ly-2/3 complex. All cultured T- and B-lymphoma lines examined were found to possess a major surface protein that appeared to be a disulfide-bonded homodimer of a polypeptide of Mr 95,000. This protein was identified as the receptor for transferrin. It is suggested that the presence of two or more subunits in cell surface receptors renders their ligand functionally bivalent, making ligand-induced receptor aggregation possible." @default.
• W2023708977 created "2016-06-24" @default.
• W2023708977 creator A5085198239 @default.
• W2023708977 creator A5091185099 @default.
• W2023708977 date "1981-07-01" @default.
• W2023708977 modified "2023-10-12" @default.
• W2023708977 title "Subunit structure of cell surface proteins: disulfide bonding in antigen receptors, Ly-2/3 antigens, and transferrin receptors of murine T and B lymphocytes." @default.
• W2023708977 cites W1488274351 @default.
• W2023708977 cites W1511330982 @default.
• W2023708977 cites W1538207147 @default.
• W2023708977 cites W1973930672 @default.
• W2023708977 cites W1981682209 @default.
• W2023708977 cites W1982754259 @default.
• W2023708977 cites W1985681534 @default.
• W2023708977 cites W2003805365 @default.
• W2023708977 cites W2010984701 @default.
• W2023708977 cites W2015113703 @default.
• W2023708977 cites W2018731804 @default.
• W2023708977 cites W2035152288 @default.
• W2023708977 cites W2041495209 @default.
• W2023708977 cites W2043701906 @default.
• W2023708977 cites W2051311496 @default.
• W2023708977 cites W2066144417 @default.
• W2023708977 cites W2070437307 @default.
• W2023708977 cites W2084546365 @default.
• W2023708977 cites W2088629685 @default.
• W2023708977 cites W2094573795 @default.
• W2023708977 cites W2104453235 @default.
• W2023708977 cites W2117138187 @default.
• W2023708977 cites W2118926353 @default.
• W2023708977 cites W2156071226 @default.
• W2023708977 cites W2161304120 @default.
• W2023708977 cites W2164358316 @default.
• W2023708977 cites W2166529851 @default.
• W2023708977 cites W2421826808 @default.
• W2023708977 cites W2463339587 @default.
• W2023708977 cites W2523129892 @default.
• W2023708977 cites W26895232 @default.
• W2023708977 doi "https://doi.org/10.1073/pnas.78.7.4530" @default.
• W2023708977 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/319825" @default.
• W2023708977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6270681" @default.
• W2023708977 hasPublicationYear "1981" @default.
• W2023708977 type Work @default.
• W2023708977 sameAs 2023708977 @default.
• W2023708977 citedByCount "69" @default.
• W2023708977 countsByYear W20237089772012 @default.
• W2023708977 countsByYear W20237089772015 @default.
• W2023708977 crossrefType "journal-article" @default.
• W2023708977 hasAuthorship W2023708977A5085198239 @default.
• W2023708977 hasAuthorship W2023708977A5091185099 @default.
• W2023708977 hasBestOaLocation W20237089772 @default.
• W2023708977 hasConcept C104292427 @default.
• W2023708977 hasConcept C104317684 @default.
• W2023708977 hasConcept C116084860 @default.
• W2023708977 hasConcept C144647389 @default.
• W2023708977 hasConcept C147483822 @default.
• W2023708977 hasConcept C153911025 @default.
• W2023708977 hasConcept C170493617 @default.
• W2023708977 hasConcept C181199279 @default.
• W2023708977 hasConcept C185592680 @default.
• W2023708977 hasConcept C203014093 @default.
• W2023708977 hasConcept C2779201268 @default.
• W2023708977 hasConcept C2910051704 @default.
• W2023708977 hasConcept C32264632 @default.
• W2023708977 hasConcept C41625074 @default.
• W2023708977 hasConcept C55493867 @default.
• W2023708977 hasConcept C71829478 @default.
• W2023708977 hasConcept C86803240 @default.
• W2023708977 hasConceptScore W2023708977C104292427 @default.
• W2023708977 hasConceptScore W2023708977C104317684 @default.
• W2023708977 hasConceptScore W2023708977C116084860 @default.
• W2023708977 hasConceptScore W2023708977C144647389 @default.
• W2023708977 hasConceptScore W2023708977C147483822 @default.
• W2023708977 hasConceptScore W2023708977C153911025 @default.
• W2023708977 hasConceptScore W2023708977C170493617 @default.
• W2023708977 hasConceptScore W2023708977C181199279 @default.
• W2023708977 hasConceptScore W2023708977C185592680 @default.
• W2023708977 hasConceptScore W2023708977C203014093 @default.
• W2023708977 hasConceptScore W2023708977C2779201268 @default.
• W2023708977 hasConceptScore W2023708977C2910051704 @default.
• W2023708977 hasConceptScore W2023708977C32264632 @default.
• W2023708977 hasConceptScore W2023708977C41625074 @default.
• W2023708977 hasConceptScore W2023708977C55493867 @default.
• W2023708977 hasConceptScore W2023708977C71829478 @default.
• W2023708977 hasConceptScore W2023708977C86803240 @default.
• W2023708977 hasIssue "7" @default.
• W2023708977 hasLocation W20237089771 @default.
• W2023708977 hasLocation W20237089772 @default.
• W2023708977 hasLocation W20237089773 @default.
• W2023708977 hasLocation W20237089774 @default.
• W2023708977 hasOpenAccess W2023708977 @default.
• W2023708977 hasPrimaryLocation W20237089771 @default.
• W2023708977 hasRelatedWork W121381176 @default.
• W2023708977 hasRelatedWork W1886974704 @default.
• W2023708977 hasRelatedWork W1976739589 @default.
• W2023708977 hasRelatedWork W2000239818 @default.
• W2023708977 hasRelatedWork W2023181098 @default.
• W2023708977 hasRelatedWork W2526890363 @default.

• next