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- W202370980 abstract "What are the prospects for physical and chemical measurements for predicting the performance of new materials in complex medical applications? Can we find relationships between the composition and structure of a biomaterial and its biological interactions, particularly in complex systems like living organisms? The reality is that physical or chemical measurements which can reliably predict in vivo biocompatibility are at this time unavailable for most biomaterials. It would be ideal to use a spectroscopic technique to measure the properties and predict how well the material will work in a particular application. Animal experiments are expensive, of questionable value for predicting performance in humans, and raise ethical issues. Human clinical trials are very expensive, and also raise ethical issues. Can we predict or prescreen in vivo or in vitro performance from measurements of surface and other physical and chemical properties? This chapter, addressing correlation, will examine this question, and offer suggestions for future exploration." @default.
- W202370980 created "2016-06-24" @default.
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- W202370980 date "2013-01-01" @default.
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- W202370980 title "Correlation, Materials Properties, Statistics and Biomaterials Science" @default.
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- W202370980 doi "https://doi.org/10.1016/b978-0-08-087780-8.00127-3" @default.
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