FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023720589> ?p ?o ?g. }

• W2023720589 endingPage "241" @default.
• W2023720589 startingPage "233" @default.
• W2023720589 abstract "The interaction of dimethyltin dichloride (Me2SnCl2) with calf thymus DNA was studied at 27 °C, pH 7.6 using various techniques including isothermal titration calorimetry (ITC) and UV-Vis, fluorescence and IR spectrophotometries. The binding isotherm and enthalpy curve for Me2SnCl2–DNA interaction was a biphasic transition process. This was determined by the analysis of the binding data with the Hill equation. The first phase of the enthalpy curve (exothermic process) was consistent with the first set of binding site, the second phase (endothermic process, less exothermicity) was consistent with second set of binding site from the cited interactions. Our results showed that the first set of binding sites is occupied by one mole of ligand bound per near 1 base pair of DNA. The DNA–ethidium bromide (EB) complex, in the presence of Me2SnCl2, caused the quenching of the fluorescence emission. The Scatchard plots illustrated a non-intercalating manner for such quenching. The DNA–EB complex results indicated that the binding of Me2SnCl2 is with the phosphate groups of DNA at low ligand concentrations (<9 mM). This was confirmed with the IR spectrophotometric spectra. However, the binding at higher ligand concentrations (>9 mM) was with the base groups of DNA. Therefore, these results suggest that the Me2SnCl2 binding to DNA at low concentrations occurs through an outside interaction by an exothermic process. However, the partial unfolding of the DNA caused at higher concentrations of Me2SnCl2 is through an endothermic process involving interactions with the base groups." @default.
• W2023720589 created "2016-06-24" @default.
• W2023720589 creator A5000362729 @default.
• W2023720589 creator A5014949604 @default.
• W2023720589 creator A5029361146 @default.
• W2023720589 creator A5059055027 @default.
• W2023720589 creator A5063432783 @default.
• W2023720589 creator A5065733999 @default.
• W2023720589 creator A5087098727 @default.
• W2023720589 date "2004-05-01" @default.
• W2023720589 modified "2023-10-17" @default.
• W2023720589 title "Microcalorimetry, energetics and binding studies of DNA–dimethyltin dichloride complexes" @default.
• W2023720589 cites W1533569014 @default.
• W2023720589 cites W1605276435 @default.
• W2023720589 cites W176210329 @default.
• W2023720589 cites W1969697214 @default.
• W2023720589 cites W1973184519 @default.
• W2023720589 cites W1974427934 @default.
• W2023720589 cites W1978880632 @default.
• W2023720589 cites W1984441606 @default.
• W2023720589 cites W1986364564 @default.
• W2023720589 cites W1988338487 @default.
• W2023720589 cites W1988693839 @default.
• W2023720589 cites W1992886533 @default.
• W2023720589 cites W1994774347 @default.
• W2023720589 cites W1997657471 @default.
• W2023720589 cites W2000549947 @default.
• W2023720589 cites W2000720737 @default.
• W2023720589 cites W2005322310 @default.
• W2023720589 cites W2008911030 @default.
• W2023720589 cites W2014588550 @default.
• W2023720589 cites W2015694743 @default.
• W2023720589 cites W2018590590 @default.
• W2023720589 cites W2026213086 @default.
• W2023720589 cites W2027583082 @default.
• W2023720589 cites W2029819107 @default.
• W2023720589 cites W2031800337 @default.
• W2023720589 cites W2039901816 @default.
• W2023720589 cites W2048208860 @default.
• W2023720589 cites W2048496500 @default.
• W2023720589 cites W2049509634 @default.
• W2023720589 cites W2049592279 @default.
• W2023720589 cites W2052793555 @default.
• W2023720589 cites W2055758448 @default.
• W2023720589 cites W2058557215 @default.
• W2023720589 cites W2062992152 @default.
• W2023720589 cites W2064441826 @default.
• W2023720589 cites W2065073846 @default.
• W2023720589 cites W2066216198 @default.
• W2023720589 cites W2068308266 @default.
• W2023720589 cites W2070247422 @default.
• W2023720589 cites W2076079790 @default.
• W2023720589 cites W2078867135 @default.
• W2023720589 cites W2082105365 @default.
• W2023720589 cites W2087207331 @default.
• W2023720589 cites W2093243028 @default.
• W2023720589 cites W2102136241 @default.
• W2023720589 cites W2113365806 @default.
• W2023720589 cites W2119831458 @default.
• W2023720589 cites W2141778672 @default.
• W2023720589 cites W2143695518 @default.
• W2023720589 cites W2146372535 @default.
• W2023720589 cites W2147938388 @default.
• W2023720589 cites W2151473259 @default.
• W2023720589 cites W2154228453 @default.
• W2023720589 cites W2209446466 @default.
• W2023720589 cites W280694366 @default.
• W2023720589 cites W2897080424 @default.
• W2023720589 doi "https://doi.org/10.1016/j.tca.2004.01.007" @default.
• W2023720589 hasPublicationYear "2004" @default.
• W2023720589 type Work @default.
• W2023720589 sameAs 2023720589 @default.
• W2023720589 citedByCount "61" @default.
• W2023720589 countsByYear W20237205892012 @default.
• W2023720589 countsByYear W20237205892014 @default.
• W2023720589 countsByYear W20237205892015 @default.
• W2023720589 countsByYear W20237205892016 @default.
• W2023720589 countsByYear W20237205892017 @default.
• W2023720589 countsByYear W20237205892018 @default.
• W2023720589 countsByYear W20237205892019 @default.
• W2023720589 countsByYear W20237205892020 @default.
• W2023720589 countsByYear W20237205892021 @default.
• W2023720589 countsByYear W20237205892022 @default.
• W2023720589 countsByYear W20237205892023 @default.
• W2023720589 crossrefType "journal-article" @default.
• W2023720589 hasAuthorship W2023720589A5000362729 @default.
• W2023720589 hasAuthorship W2023720589A5014949604 @default.
• W2023720589 hasAuthorship W2023720589A5029361146 @default.
• W2023720589 hasAuthorship W2023720589A5059055027 @default.
• W2023720589 hasAuthorship W2023720589A5063432783 @default.
• W2023720589 hasAuthorship W2023720589A5065733999 @default.
• W2023720589 hasAuthorship W2023720589A5087098727 @default.
• W2023720589 hasConcept C107824862 @default.
• W2023720589 hasConcept C116569031 @default.
• W2023720589 hasConcept C121332964 @default.
• W2023720589 hasConcept C121745418 @default.
• W2023720589 hasConcept C137824038 @default.
• W2023720589 hasConcept C147789679 @default.

• next