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- W2023724749 abstract "A rapid, sensitive, and reproducible reverse phase high performance liquid chromatographic (RP-HPLC) method with UV detector for the determination of nimodipine in sustained release tablets was developed. The method involved using a SinoChoom ODS-BP C 18 reversed phase column (5 μ m, 4.6 mm × 200 mm) and mobile phase consisting of methanol-acetonitrile-water (35 : 38 : 27, v/v). The flow rate is 1.0 mL/min, the UV detector was operated at 237 nm, and the column was maintained at 25°C. The method was validated according to official compendia guidelines. The calibration curve of nimodipine for RP-HPLC method was linear over the range of 10–100 μ g/mL. The retention time was found at 7.50 min for nimodipine. The variation for interday and intraday assay was found to be less than 0.72%. The proposed RP-HPLC was proved to be suitable for the determination of nimodipine in sustained release tablets." @default.
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- W2023724749 date "2013-01-01" @default.
- W2023724749 modified "2023-09-23" @default.
- W2023724749 title "Development and Validation of a RP-HPLC Method for Determination of Nimodipine in Sustained Release Tablets" @default.
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- W2023724749 doi "https://doi.org/10.1155/2013/612082" @default.
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