FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023728048> ?p ?o ?g. }

• W2023728048 endingPage "250" @default.
• W2023728048 startingPage "241" @default.
• W2023728048 abstract "A generic method is described to form poorly water-soluble drug nanoparticles within water-soluble porous polymer by solvent evaporation. The simple dissolution of porous polymer with drug nanoparticles results in stable aqueous drug nanoparticle suspension under the optimized conditions. The porous polymers were prepared by freeze-drying aqueous solutions of polyvinyl alcohol, polyethylene glycol, and a surfactant. They were then used as scaffolds for the formation of nanoparticles by initially soaking them in an organic drug solution, followed with removing the solvent via evaporation under ambient conditions. This process was optimized for an antifungal drug griseofulvin, before being translated to anticonvulsant carbamazepine and antineoplastic paclitaxel via a similar procedure, with an aim to improve the loading of drug nanoparticles. By varying certain process parameters a degree of control over the particle size and surface charge could be attained, as well as the drug to stabilizer ratio (drug payload). Noticeably, aqueous paclitaxel nanoparticles (500 nm) were prepared which used the equivalent of 46% less stabilizer than the formulation Taxol®." @default.
• W2023728048 created "2016-06-24" @default.
• W2023728048 creator A5066165164 @default.
• W2023728048 creator A5077212897 @default.
• W2023728048 date "2013-04-01" @default.
• W2023728048 modified "2023-10-14" @default.
• W2023728048 title "Poorly water-soluble drug nanoparticles via solvent evaporation in water-soluble porous polymers" @default.
• W2023728048 cites W1968900010 @default.
• W2023728048 cites W1971181330 @default.
• W2023728048 cites W1978500530 @default.
• W2023728048 cites W1981531730 @default.
• W2023728048 cites W1991525295 @default.
• W2023728048 cites W1993543954 @default.
• W2023728048 cites W1994269711 @default.
• W2023728048 cites W2000924336 @default.
• W2023728048 cites W2002975193 @default.
• W2023728048 cites W2004048086 @default.
• W2023728048 cites W2004639120 @default.
• W2023728048 cites W2013339162 @default.
• W2023728048 cites W2013662870 @default.
• W2023728048 cites W2015230924 @default.
• W2023728048 cites W2022935230 @default.
• W2023728048 cites W2026930707 @default.
• W2023728048 cites W2028031583 @default.
• W2023728048 cites W2037048276 @default.
• W2023728048 cites W2038526752 @default.
• W2023728048 cites W2044647958 @default.
• W2023728048 cites W2046383628 @default.
• W2023728048 cites W2050528759 @default.
• W2023728048 cites W2058686392 @default.
• W2023728048 cites W2059225643 @default.
• W2023728048 cites W2067883373 @default.
• W2023728048 cites W2070545569 @default.
• W2023728048 cites W2076858446 @default.
• W2023728048 cites W2078775260 @default.
• W2023728048 cites W2078814811 @default.
• W2023728048 cites W2083677006 @default.
• W2023728048 cites W2083710155 @default.
• W2023728048 cites W2094825236 @default.
• W2023728048 cites W2100520064 @default.
• W2023728048 cites W2103768330 @default.
• W2023728048 cites W2109106318 @default.
• W2023728048 cites W2126077921 @default.
• W2023728048 cites W2127059943 @default.
• W2023728048 cites W2171682018 @default.
• W2023728048 cites W2171792381 @default.
• W2023728048 cites W2184694295 @default.
• W2023728048 doi "https://doi.org/10.1016/j.ijpharm.2013.03.001" @default.
• W2023728048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23499755" @default.
• W2023728048 hasPublicationYear "2013" @default.
• W2023728048 type Work @default.
• W2023728048 sameAs 2023728048 @default.
• W2023728048 citedByCount "26" @default.
• W2023728048 countsByYear W20237280482013 @default.
• W2023728048 countsByYear W20237280482014 @default.
• W2023728048 countsByYear W20237280482015 @default.
• W2023728048 countsByYear W20237280482016 @default.
• W2023728048 countsByYear W20237280482017 @default.
• W2023728048 countsByYear W20237280482018 @default.
• W2023728048 countsByYear W20237280482019 @default.
• W2023728048 countsByYear W20237280482020 @default.
• W2023728048 countsByYear W20237280482022 @default.
• W2023728048 crossrefType "journal-article" @default.
• W2023728048 hasAuthorship W2023728048A5066165164 @default.
• W2023728048 hasAuthorship W2023728048A5077212897 @default.
• W2023728048 hasConcept C121332964 @default.
• W2023728048 hasConcept C127413603 @default.
• W2023728048 hasConcept C13245373 @default.
• W2023728048 hasConcept C142724271 @default.
• W2023728048 hasConcept C155672457 @default.
• W2023728048 hasConcept C171250308 @default.
• W2023728048 hasConcept C178790620 @default.
• W2023728048 hasConcept C184651966 @default.
• W2023728048 hasConcept C185592680 @default.
• W2023728048 hasConcept C187530423 @default.
• W2023728048 hasConcept C192562407 @default.
• W2023728048 hasConcept C2776964284 @default.
• W2023728048 hasConcept C2778551929 @default.
• W2023728048 hasConcept C2779819575 @default.
• W2023728048 hasConcept C2779820397 @default.
• W2023728048 hasConcept C2780471494 @default.
• W2023728048 hasConcept C42360764 @default.
• W2023728048 hasConcept C521977710 @default.
• W2023728048 hasConcept C61441594 @default.
• W2023728048 hasConcept C71924100 @default.
• W2023728048 hasConcept C88380143 @default.
• W2023728048 hasConcept C97355855 @default.
• W2023728048 hasConceptScore W2023728048C121332964 @default.
• W2023728048 hasConceptScore W2023728048C127413603 @default.
• W2023728048 hasConceptScore W2023728048C13245373 @default.
• W2023728048 hasConceptScore W2023728048C142724271 @default.
• W2023728048 hasConceptScore W2023728048C155672457 @default.
• W2023728048 hasConceptScore W2023728048C171250308 @default.
• W2023728048 hasConceptScore W2023728048C178790620 @default.
• W2023728048 hasConceptScore W2023728048C184651966 @default.
• W2023728048 hasConceptScore W2023728048C185592680 @default.
• W2023728048 hasConceptScore W2023728048C187530423 @default.
• W2023728048 hasConceptScore W2023728048C192562407 @default.

• next