Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023730968> ?p ?o ?g. }
- W2023730968 endingPage "11636" @default.
- W2023730968 startingPage "11624" @default.
- W2023730968 abstract "There are many examples of neuronal coupling via gap junctions in the retina. Of these, perhaps the best known is the extensive coupling between horizontal cells. In the rabbit retina, there are two types of horizontal cells, A-type and B-type, both of which are independently coupled. Connexin 50 (Cx50) cDNA, encoding a 440 aa protein, was successfully isolated from rabbit retina RNA. Cx50 was also obtained from isolated A-type horizontal cells (A-type HCs) by single-cell RT-PCR. A-type HCs were visualized by intracellular dye injection or with an antibody against calbindin. Confocal analysis revealed all Cx50 labeling occurred on the A-type HC matrix, typically at dendritic intersections. The Cx50 plaques varied in size, from punctate signals in which fine dendrites cofasciculated, to giant plaques, >50 μm 2 , in which large dendrites crossed. The numerous Cx50 plaques between A-type HCs may adequately account for the remarkable coupling observed in this network. We could not detect Cx50 staining on the tips of horizontal cell dendrites within the cone pedicle invagination. This distribution does not support a role for Cx50 in hemichannel-mediated feedback. In addition, the absence of Cx50 in B-type HCs suggests the presence of a different connexin for this cell type. In summary, these results suggest that gap junctions in the A-type horizontal cell matrix are composed from Cx50. Multiple neuronal connexins are expressed in the mammalian retina and different cell types express specific connexins." @default.
- W2023730968 created "2016-06-24" @default.
- W2023730968 creator A5000432967 @default.
- W2023730968 creator A5014796170 @default.
- W2023730968 creator A5031683516 @default.
- W2023730968 creator A5064044258 @default.
- W2023730968 creator A5081186684 @default.
- W2023730968 creator A5091178282 @default.
- W2023730968 date "2006-11-08" @default.
- W2023730968 modified "2023-10-18" @default.
- W2023730968 title "Coupling between A-Type Horizontal Cells Is Mediated by Connexin 50 Gap Junctions in the Rabbit Retina" @default.
- W2023730968 cites W1637869366 @default.
- W2023730968 cites W1660125060 @default.
- W2023730968 cites W1874635627 @default.
- W2023730968 cites W1964702556 @default.
- W2023730968 cites W1967949725 @default.
- W2023730968 cites W1968411842 @default.
- W2023730968 cites W1972856758 @default.
- W2023730968 cites W1978359413 @default.
- W2023730968 cites W1978599626 @default.
- W2023730968 cites W1981613176 @default.
- W2023730968 cites W1982236694 @default.
- W2023730968 cites W1982524452 @default.
- W2023730968 cites W1982535090 @default.
- W2023730968 cites W1984987212 @default.
- W2023730968 cites W1985768427 @default.
- W2023730968 cites W1986027019 @default.
- W2023730968 cites W1995419973 @default.
- W2023730968 cites W2002649438 @default.
- W2023730968 cites W2003564852 @default.
- W2023730968 cites W2005060282 @default.
- W2023730968 cites W2008813184 @default.
- W2023730968 cites W2009133239 @default.
- W2023730968 cites W2017203200 @default.
- W2023730968 cites W2017649359 @default.
- W2023730968 cites W2018413008 @default.
- W2023730968 cites W2018503640 @default.
- W2023730968 cites W2018782802 @default.
- W2023730968 cites W2019156585 @default.
- W2023730968 cites W2021739229 @default.
- W2023730968 cites W2026011339 @default.
- W2023730968 cites W2028290043 @default.
- W2023730968 cites W2030769731 @default.
- W2023730968 cites W2031938763 @default.
- W2023730968 cites W2037249551 @default.
- W2023730968 cites W2042205780 @default.
- W2023730968 cites W2042890989 @default.
- W2023730968 cites W2043654463 @default.
- W2023730968 cites W2043931511 @default.
- W2023730968 cites W2044959126 @default.
- W2023730968 cites W2046297486 @default.
- W2023730968 cites W2048684386 @default.
- W2023730968 cites W2067143949 @default.
- W2023730968 cites W2070696598 @default.
- W2023730968 cites W2075214952 @default.
- W2023730968 cites W2075822428 @default.
- W2023730968 cites W2076945701 @default.
- W2023730968 cites W2077845955 @default.
- W2023730968 cites W2084051175 @default.
- W2023730968 cites W2087361927 @default.
- W2023730968 cites W2089275735 @default.
- W2023730968 cites W2090093046 @default.
- W2023730968 cites W2091572804 @default.
- W2023730968 cites W2092164782 @default.
- W2023730968 cites W2094529924 @default.
- W2023730968 cites W2117496050 @default.
- W2023730968 cites W2122348590 @default.
- W2023730968 cites W2123165969 @default.
- W2023730968 cites W2125002589 @default.
- W2023730968 cites W2128261107 @default.
- W2023730968 cites W2133952757 @default.
- W2023730968 cites W2138036850 @default.
- W2023730968 cites W2138864044 @default.
- W2023730968 cites W2144556755 @default.
- W2023730968 cites W2150899253 @default.
- W2023730968 cites W2157988319 @default.
- W2023730968 cites W2342055393 @default.
- W2023730968 doi "https://doi.org/10.1523/jneurosci.2296-06.2006" @default.
- W2023730968 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6674794" @default.
- W2023730968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17093084" @default.
- W2023730968 hasPublicationYear "2006" @default.
- W2023730968 type Work @default.
- W2023730968 sameAs 2023730968 @default.
- W2023730968 citedByCount "62" @default.
- W2023730968 countsByYear W20237309682012 @default.
- W2023730968 countsByYear W20237309682013 @default.
- W2023730968 countsByYear W20237309682014 @default.
- W2023730968 countsByYear W20237309682015 @default.
- W2023730968 countsByYear W20237309682016 @default.
- W2023730968 countsByYear W20237309682017 @default.
- W2023730968 countsByYear W20237309682018 @default.
- W2023730968 countsByYear W20237309682019 @default.
- W2023730968 countsByYear W20237309682020 @default.
- W2023730968 countsByYear W20237309682022 @default.
- W2023730968 countsByYear W20237309682023 @default.
- W2023730968 crossrefType "journal-article" @default.
- W2023730968 hasAuthorship W2023730968A5000432967 @default.
- W2023730968 hasAuthorship W2023730968A5014796170 @default.