FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023732275> ?p ?o ?g. }

• W2023732275 endingPage "549" @default.
• W2023732275 startingPage "539" @default.
• W2023732275 abstract "Abstract Four species of 1SS‐varinats of lysozyme were almost unstructured in water, judged from their near‐UV CD and 1 H‐ 15 N‐HSQC spectra. Some preferential structure might exist in such a disordered state, but the population of molecules in such a conformation must have been too small to be detected by spectroscopic methods. Indeed, our previous study showed that the addition of 30% glycerol induced the unstructured 2SS‐variant of lysozyme to form a native‐like structure. To extend this method to more disordered proteins, we attempted to detect some preferential structure latent in unstructured 1SS‐variants by the glycerol‐enhanced detection. Only in one molecular species of the four 1SS‐variants, 1SS[6‐127] containing a single disulfide bridge of Cys6‐Cys127, a preferential structure was found in the presence of 50% glycerol. It was detected by near‐UV CD measurements and the H/D exchange method combined with the NMR spectroscopy. The glycerol‐induced structure in 1SS[6‐127] was not localized only in the vicinity of Cys6‐Cys127, and largely protected regions distributed themselves among A‐, B‐, and C‐helices and Ile55 and Leu56. It was similar to the glycerol‐induced structure in 2SS[6‐127, 64‐80] containing two disulfide bridges of Cys6‐Cys127 and Cys64‐Cys80, although the former was less rigid than the latter. The role of A‐helix (residues 4–15) is proposed as an origin of excellent potential of Cys6‐Cys127 for inducing a tertiary structure in the α‐domain. © 2012 Wiley Periodicals, Inc. Biopolymers 97:539–549, 2012." @default.
• W2023732275 created "2016-06-24" @default.
• W2023732275 creator A5005339438 @default.
• W2023732275 creator A5014756582 @default.
• W2023732275 creator A5039623511 @default.
• W2023732275 creator A5044942161 @default.
• W2023732275 creator A5090902825 @default.
• W2023732275 date "2012-02-18" @default.
• W2023732275 modified "2023-10-16" @default.
• W2023732275 title "Glycerol-enhanced detection of a preferential structure latent in unstructured 1SS-variants of lysozyme" @default.
• W2023732275 cites W1977325148 @default.
• W2023732275 cites W1980388661 @default.
• W2023732275 cites W1982762997 @default.
• W2023732275 cites W1984122795 @default.
• W2023732275 cites W1993703672 @default.
• W2023732275 cites W2000879491 @default.
• W2023732275 cites W2005246178 @default.
• W2023732275 cites W2006799495 @default.
• W2023732275 cites W2008644016 @default.
• W2023732275 cites W2012537685 @default.
• W2023732275 cites W2028289026 @default.
• W2023732275 cites W2029667189 @default.
• W2023732275 cites W2033047796 @default.
• W2023732275 cites W2035472706 @default.
• W2023732275 cites W2038120407 @default.
• W2023732275 cites W2043750499 @default.
• W2023732275 cites W2044483297 @default.
• W2023732275 cites W2045589999 @default.
• W2023732275 cites W2049876291 @default.
• W2023732275 cites W2051436197 @default.
• W2023732275 cites W2068227670 @default.
• W2023732275 cites W2072738515 @default.
• W2023732275 cites W2076295853 @default.
• W2023732275 cites W2078916999 @default.
• W2023732275 cites W2081531609 @default.
• W2023732275 cites W2087579391 @default.
• W2023732275 cites W2089499652 @default.
• W2023732275 cites W2101493587 @default.
• W2023732275 cites W2123170797 @default.
• W2023732275 cites W2128088132 @default.
• W2023732275 cites W2149406325 @default.
• W2023732275 doi "https://doi.org/10.1002/bip.22037" @default.
• W2023732275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22344587" @default.
• W2023732275 hasPublicationYear "2012" @default.
• W2023732275 type Work @default.
• W2023732275 sameAs 2023732275 @default.
• W2023732275 citedByCount "2" @default.
• W2023732275 countsByYear W20237322752013 @default.
• W2023732275 countsByYear W20237322752015 @default.
• W2023732275 crossrefType "journal-article" @default.
• W2023732275 hasAuthorship W2023732275A5005339438 @default.
• W2023732275 hasAuthorship W2023732275A5014756582 @default.
• W2023732275 hasAuthorship W2023732275A5039623511 @default.
• W2023732275 hasAuthorship W2023732275A5044942161 @default.
• W2023732275 hasAuthorship W2023732275A5090902825 @default.
• W2023732275 hasConcept C178790620 @default.
• W2023732275 hasConcept C185592680 @default.
• W2023732275 hasConcept C18903297 @default.
• W2023732275 hasConcept C2776966407 @default.
• W2023732275 hasConcept C2778530040 @default.
• W2023732275 hasConcept C2779965526 @default.
• W2023732275 hasConcept C2780881558 @default.
• W2023732275 hasConcept C32909587 @default.
• W2023732275 hasConcept C55493867 @default.
• W2023732275 hasConcept C62614982 @default.
• W2023732275 hasConcept C71240020 @default.
• W2023732275 hasConcept C8010536 @default.
• W2023732275 hasConcept C86803240 @default.
• W2023732275 hasConceptScore W2023732275C178790620 @default.
• W2023732275 hasConceptScore W2023732275C185592680 @default.
• W2023732275 hasConceptScore W2023732275C18903297 @default.
• W2023732275 hasConceptScore W2023732275C2776966407 @default.
• W2023732275 hasConceptScore W2023732275C2778530040 @default.
• W2023732275 hasConceptScore W2023732275C2779965526 @default.
• W2023732275 hasConceptScore W2023732275C2780881558 @default.
• W2023732275 hasConceptScore W2023732275C32909587 @default.
• W2023732275 hasConceptScore W2023732275C55493867 @default.
• W2023732275 hasConceptScore W2023732275C62614982 @default.
• W2023732275 hasConceptScore W2023732275C71240020 @default.
• W2023732275 hasConceptScore W2023732275C8010536 @default.
• W2023732275 hasConceptScore W2023732275C86803240 @default.
• W2023732275 hasIssue "7" @default.
• W2023732275 hasLocation W20237322751 @default.
• W2023732275 hasLocation W20237322752 @default.
• W2023732275 hasOpenAccess W2023732275 @default.
• W2023732275 hasPrimaryLocation W20237322751 @default.
• W2023732275 hasRelatedWork W1541765418 @default.
• W2023732275 hasRelatedWork W2067924147 @default.
• W2023732275 hasRelatedWork W2091626861 @default.
• W2023732275 hasRelatedWork W2314385229 @default.
• W2023732275 hasRelatedWork W2368942211 @default.
• W2023732275 hasRelatedWork W2382247014 @default.
• W2023732275 hasRelatedWork W2441126129 @default.
• W2023732275 hasRelatedWork W2914878125 @default.
• W2023732275 hasRelatedWork W3000432101 @default.
• W2023732275 hasRelatedWork W1913424772 @default.
• W2023732275 hasVolume "97" @default.
• W2023732275 isParatext "false" @default.

• next