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- W2023736349 abstract "Both adaptive and innate immune systems are involved in coronary artery disease (CAD). The aim of this study was to evaluate TH17 cytokines expression profiles in un-stimulated peripheral blood lymphocytes (PBMCs) of patients with coronary artery disease.Expression profiles of IL-17, IL-23, and TGF-β1 were determined in individuals with and without CAD using Real-time PCR.A significant decrease in IL-23 gene expression in un-stimulated PBMCs of patients with CAD compared to those without CAD was found (p=0.003, OR=0.045, 95% CI: 0.006-0.355).Our data reinforce the potential role of the IL-23 as a critical regulatory molecule that bridges the innate and adaptive arms of the immune system in the complex mechanisms associated with the development of atherosclerosis." @default.
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- W2023736349 date "2012-01-01" @default.
- W2023736349 modified "2023-09-27" @default.
- W2023736349 title "IL-23 gene expression in PBMCs of patients with coronary artery disease." @default.
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- W2023736349 doi "https://doi.org/10.3233/dma-2012-00933" @default.
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