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- W2023741946 abstract "Pharmacological properties of a crude saponin fraction (GF-DS-I) and saponins (GF-DS-II) which were obtained from Panax Ginseng leaves, were estimated by blind screening consisting of three tests: 1) neuropharmacological observations in mice, 2) tests on the respiratory and cardiovascular system in rats, and 3) tests on the guinea-pig isolated ileum. GF-DS-I appeared to have CNS-depressive, neuroleptic, analgesic, hypertensive, cholinergic, and histamine-like activities, while GF-DS-II, had CNS-depressive, neuroleptic, analgesic, hypotensive, atropine-like and papaverine-like activities. These neuroleptic activities, were examined and confirmed by tests on motor activity, exploratory movements, muscle tone, motor coordination, hypothermia and potentiation of CNS-depressant, and pole climbing, anticonvulsant and analgesic tests. No effects were seen on hemolysis." @default.
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- W2023741946 date "1973-01-01" @default.
- W2023741946 modified "2023-10-03" @default.
- W2023741946 title "PHARMACOLOGICAL STUDIES OF PANAX GINSENG LEAVES" @default.
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- W2023741946 doi "https://doi.org/10.1254/jjp.23.43" @default.
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