FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023746097> ?p ?o ?g. }

• W2023746097 endingPage "553" @default.
• W2023746097 startingPage "543" @default.
• W2023746097 abstract "Many investigations about the cellular response by metal oxide nanoparticles in vitro have been reported. However, the influence of the adsorption ability of metal oxide nanoparticles toward cells is unknown. The aim of this study is to understand the influence of adsorption by metal oxide nanoparticles on the cell viability in vitro. The adsorption abilities of six kinds of metal oxide nanoparticles, namely, NiO, ZnO, TiO2, CeO2, SiO2, and Fe2O3, to Dulbecco's modified Eagle's medium supplemented with a 10% fetal bovine serum (DMEM-FBS) component such as serum proteins and Ca2) were estimated. All of the metal oxide nanoparticles adsorbed proteins and Ca2+ in the DMEM-FBS; in particular, TiO2, CeO2, and ZnO showed strong adsorption abilities. Furthermore, the influence of the depletion of medium components by adsorption to metal oxide nanoparticles on cell viability and proliferation was examined. The particles were removed from the dispersion by centrifugation, and the supernatant was applied to the cells. Both the cell viability and the proliferation of human keratinocyte HaCaT cells and human lung carcinoma A549 cells were affected by the supernatant. In particular, cell proliferation was strongly inhibited by the supernatant of TiO2 and CeO2 dispersions. The supernatant showed depletion of serum proteins and Ca2+ by adsorption to metal oxide nanoparticles. When the adsorption effect was blocked by the pretreatment of particles with FBS, the inhibitory effect was lost. However, in NiO and ZnO, which showed ion release, a decrease of inhibitory effect by pretreatment was not shown. Furthermore, the association of the primary particle size and adsorption ability was examined in TiO2. The adsorption ability of TiO2 depended on the primary particle size. The TiO2 nanoparticles were size dependently absorbed with proteins and Ca2+, thereby inducing cytotoxicity. In conclusion, the adsorption ability of metal oxide nanoparticles is an important factor for the estimation of cytotoxicity in vitro for low-toxicity materials." @default.
• W2023746097 created "2016-06-24" @default.
• W2023746097 creator A5002884475 @default.
• W2023746097 creator A5006088554 @default.
• W2023746097 creator A5013822607 @default.
• W2023746097 creator A5021883223 @default.
• W2023746097 creator A5026184610 @default.
• W2023746097 creator A5045319194 @default.
• W2023746097 creator A5047847394 @default.
• W2023746097 creator A5051638201 @default.
• W2023746097 creator A5062876989 @default.
• W2023746097 creator A5068391520 @default.
• W2023746097 creator A5079468649 @default.
• W2023746097 creator A5082049959 @default.
• W2023746097 creator A5083817484 @default.
• W2023746097 date "2009-02-16" @default.
• W2023746097 modified "2023-10-16" @default.
• W2023746097 title "Protein Adsorption of Ultrafine Metal Oxide and Its Influence on Cytotoxicity toward Cultured Cells" @default.
• W2023746097 cites W1504792186 @default.
• W2023746097 cites W1966476051 @default.
• W2023746097 cites W1978653530 @default.
• W2023746097 cites W1981893357 @default.
• W2023746097 cites W1988503311 @default.
• W2023746097 cites W1989335240 @default.
• W2023746097 cites W1997215103 @default.
• W2023746097 cites W2003176944 @default.
• W2023746097 cites W2004089934 @default.
• W2023746097 cites W2005883236 @default.
• W2023746097 cites W2021712303 @default.
• W2023746097 cites W2023785357 @default.
• W2023746097 cites W2025188006 @default.
• W2023746097 cites W2030071612 @default.
• W2023746097 cites W2037831947 @default.
• W2023746097 cites W2046404608 @default.
• W2023746097 cites W2048981263 @default.
• W2023746097 cites W2049271296 @default.
• W2023746097 cites W2051361096 @default.
• W2023746097 cites W2052879757 @default.
• W2023746097 cites W2071396517 @default.
• W2023746097 cites W2099191918 @default.
• W2023746097 cites W2110639369 @default.
• W2023746097 cites W2117326659 @default.
• W2023746097 cites W2120579564 @default.
• W2023746097 cites W2122284189 @default.
• W2023746097 cites W2126008809 @default.
• W2023746097 cites W2129384155 @default.
• W2023746097 cites W2129637849 @default.
• W2023746097 cites W2132221116 @default.
• W2023746097 cites W2132834292 @default.
• W2023746097 cites W2135488990 @default.
• W2023746097 cites W2140720810 @default.
• W2023746097 cites W2147564235 @default.
• W2023746097 cites W2148293029 @default.
• W2023746097 cites W2149848619 @default.
• W2023746097 cites W2155118487 @default.
• W2023746097 cites W2157489799 @default.
• W2023746097 cites W2159364645 @default.
• W2023746097 cites W4232534952 @default.
• W2023746097 doi "https://doi.org/10.1021/tx800289z" @default.
• W2023746097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19216582" @default.
• W2023746097 hasPublicationYear "2009" @default.
• W2023746097 type Work @default.
• W2023746097 sameAs 2023746097 @default.
• W2023746097 citedByCount "249" @default.
• W2023746097 countsByYear W20237460972012 @default.
• W2023746097 countsByYear W20237460972013 @default.
• W2023746097 countsByYear W20237460972014 @default.
• W2023746097 countsByYear W20237460972015 @default.
• W2023746097 countsByYear W20237460972016 @default.
• W2023746097 countsByYear W20237460972017 @default.
• W2023746097 countsByYear W20237460972018 @default.
• W2023746097 countsByYear W20237460972019 @default.
• W2023746097 countsByYear W20237460972020 @default.
• W2023746097 countsByYear W20237460972021 @default.
• W2023746097 countsByYear W20237460972022 @default.
• W2023746097 countsByYear W20237460972023 @default.
• W2023746097 crossrefType "journal-article" @default.
• W2023746097 hasAuthorship W2023746097A5002884475 @default.
• W2023746097 hasAuthorship W2023746097A5006088554 @default.
• W2023746097 hasAuthorship W2023746097A5013822607 @default.
• W2023746097 hasAuthorship W2023746097A5021883223 @default.
• W2023746097 hasAuthorship W2023746097A5026184610 @default.
• W2023746097 hasAuthorship W2023746097A5045319194 @default.
• W2023746097 hasAuthorship W2023746097A5047847394 @default.
• W2023746097 hasAuthorship W2023746097A5051638201 @default.
• W2023746097 hasAuthorship W2023746097A5062876989 @default.
• W2023746097 hasAuthorship W2023746097A5068391520 @default.
• W2023746097 hasAuthorship W2023746097A5079468649 @default.
• W2023746097 hasAuthorship W2023746097A5082049959 @default.
• W2023746097 hasAuthorship W2023746097A5083817484 @default.
• W2023746097 hasConcept C109316439 @default.
• W2023746097 hasConcept C118995209 @default.
• W2023746097 hasConcept C12554922 @default.
• W2023746097 hasConcept C13965031 @default.
• W2023746097 hasConcept C150394285 @default.
• W2023746097 hasConcept C155672457 @default.
• W2023746097 hasConcept C171250308 @default.
• W2023746097 hasConcept C178790620 @default.

• next