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• W2023746965 abstract "In vitro, differential pulse voltammetry combined with electrochemically treated carbon fiber electrodes enabled detection, in different solution of 5-hydroxyindole compounds, of an oxidation peak 3 at +300 mV. In vivo, a striatal peak 3 was also recorded at this potential. Electrolytic or 5,7-dihydroxytryptamine lesions interrupting the medial forebrain bundle (MFB) were followed by a decrease of 65% and 64% in peak height, but not elimination of the peak. Biochemical determinations were significantly correlated to the peak 3 measurements. The existence of peak 3 as well as hydroxyindole compounds in blood suggested a blood contamination under the experimental conditions employed. This possibility is confirmed both by the complete disappearance of striatal peak 3 in animals with the MFB lesioned and surgically prepared a week before recordings, and by biochemical measurements in parachlorophenylalanine-treated or perfused (phosphate-buffered saline solution) animals." @default.
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• W2023746965 date "1981-11-01" @default.
• W2023746965 modified "2023-10-16" @default.
• W2023746965 title "Differential pulse voltammetry in brain tissue. I. Detection of 5-hydroxyindoles in the rat striatum" @default.
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• W2023746965 doi "https://doi.org/10.1016/0006-8993(81)91142-2" @default.
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