FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023752458> ?p ?o ?g. }

• W2023752458 endingPage "456" @default.
• W2023752458 startingPage "440" @default.
• W2023752458 abstract "Interest in biomarkers in the field of thoracic oncology is focused on the search for new robust tests for diagnosis (in particular for screening), prognosis and theragnosis. These biomarkers can be detected in tissues and/or cells, but also in biological fluids, mainly the blood. In this context, there is growing interest in the detection of circulating tumor cells (CTCs) in the blood of lung cancer patients since CTC identification, enumeration and characterization may have a direct impact on diagnosis, prognosis and theragnosis in the daily clinical practice. Many direct and indirect methods have been developed to detect and characterize CTCs in lung cancer patients. However, these different approaches still hold limitations and many of them have demonstrated unequal sensitivity and specificity. Indeed, these methods hold advantages but also certain disadvantages. Therefore, despite the promises, it is currently difficult and premature to apply this methodology to the routine care of lung cancer patients. This situation is the consequence of the analysis of the methodological approaches for the detection and characterization of CTCs and of the results published to date. Finally, the advent of targeted cancer therapies in thoracic oncology has stimulated considerable interest in non-invasive detection of genomic alterations in tumors over time through the analysis of CTCs, an approach that may help clinicians to optimize therapeutic strategies for lung cancer patients. We describe here the main methods for CTC detection, the advantages and limitations of these different approaches and the potential usefulness and value of CTC characterization in the field of thoracic oncology. Keywords: Cancer screening, circulating tumor cells, diagnosis, lung cancer, personalized medicine, prognosis, targeted therapy." @default.
• W2023752458 created "2016-06-24" @default.
• W2023752458 creator A5002597256 @default.
• W2023752458 creator A5004580403 @default.
• W2023752458 creator A5023825873 @default.
• W2023752458 creator A5026960297 @default.
• W2023752458 creator A5028693753 @default.
• W2023752458 creator A5029463040 @default.
• W2023752458 creator A5029520265 @default.
• W2023752458 creator A5036364955 @default.
• W2023752458 creator A5046991850 @default.
• W2023752458 creator A5049562438 @default.
• W2023752458 creator A5055246540 @default.
• W2023752458 creator A5057863650 @default.
• W2023752458 creator A5059366356 @default.
• W2023752458 creator A5082924156 @default.
• W2023752458 creator A5090050048 @default.
• W2023752458 date "2014-05-31" @default.
• W2023752458 modified "2023-10-18" @default.
• W2023752458 title "Detection of Circulating Tumor Cells from Lung Cancer Patients in the Era of Targeted Therapy : Promises, Drawbacks and Pitfalls" @default.
• W2023752458 doi "https://doi.org/10.2174/1566524014666140414205455" @default.
• W2023752458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24730524" @default.
• W2023752458 hasPublicationYear "2014" @default.
• W2023752458 type Work @default.
• W2023752458 sameAs 2023752458 @default.
• W2023752458 citedByCount "54" @default.
• W2023752458 countsByYear W20237524582014 @default.
• W2023752458 countsByYear W20237524582015 @default.
• W2023752458 countsByYear W20237524582016 @default.
• W2023752458 countsByYear W20237524582017 @default.
• W2023752458 countsByYear W20237524582018 @default.
• W2023752458 countsByYear W20237524582019 @default.
• W2023752458 countsByYear W20237524582020 @default.
• W2023752458 countsByYear W20237524582021 @default.
• W2023752458 countsByYear W20237524582022 @default.
• W2023752458 countsByYear W20237524582023 @default.
• W2023752458 crossrefType "journal-article" @default.
• W2023752458 hasAuthorship W2023752458A5002597256 @default.
• W2023752458 hasAuthorship W2023752458A5004580403 @default.
• W2023752458 hasAuthorship W2023752458A5023825873 @default.
• W2023752458 hasAuthorship W2023752458A5026960297 @default.
• W2023752458 hasAuthorship W2023752458A5028693753 @default.
• W2023752458 hasAuthorship W2023752458A5029463040 @default.
• W2023752458 hasAuthorship W2023752458A5029520265 @default.
• W2023752458 hasAuthorship W2023752458A5036364955 @default.
• W2023752458 hasAuthorship W2023752458A5046991850 @default.
• W2023752458 hasAuthorship W2023752458A5049562438 @default.
• W2023752458 hasAuthorship W2023752458A5055246540 @default.
• W2023752458 hasAuthorship W2023752458A5057863650 @default.
• W2023752458 hasAuthorship W2023752458A5059366356 @default.
• W2023752458 hasAuthorship W2023752458A5082924156 @default.
• W2023752458 hasAuthorship W2023752458A5090050048 @default.
• W2023752458 hasConcept C121608353 @default.
• W2023752458 hasConcept C126322002 @default.
• W2023752458 hasConcept C142724271 @default.
• W2023752458 hasConcept C143998085 @default.
• W2023752458 hasConcept C151730666 @default.
• W2023752458 hasConcept C163763905 @default.
• W2023752458 hasConcept C177713679 @default.
• W2023752458 hasConcept C2776256026 @default.
• W2023752458 hasConcept C2779013556 @default.
• W2023752458 hasConcept C2779343474 @default.
• W2023752458 hasConcept C2781230642 @default.
• W2023752458 hasConcept C61238886 @default.
• W2023752458 hasConcept C71924100 @default.
• W2023752458 hasConcept C86803240 @default.
• W2023752458 hasConceptScore W2023752458C121608353 @default.
• W2023752458 hasConceptScore W2023752458C126322002 @default.
• W2023752458 hasConceptScore W2023752458C142724271 @default.
• W2023752458 hasConceptScore W2023752458C143998085 @default.
• W2023752458 hasConceptScore W2023752458C151730666 @default.
• W2023752458 hasConceptScore W2023752458C163763905 @default.
• W2023752458 hasConceptScore W2023752458C177713679 @default.
• W2023752458 hasConceptScore W2023752458C2776256026 @default.
• W2023752458 hasConceptScore W2023752458C2779013556 @default.
• W2023752458 hasConceptScore W2023752458C2779343474 @default.
• W2023752458 hasConceptScore W2023752458C2781230642 @default.
• W2023752458 hasConceptScore W2023752458C61238886 @default.
• W2023752458 hasConceptScore W2023752458C71924100 @default.
• W2023752458 hasConceptScore W2023752458C86803240 @default.
• W2023752458 hasIssue "4" @default.
• W2023752458 hasLocation W20237524581 @default.
• W2023752458 hasLocation W20237524582 @default.
• W2023752458 hasOpenAccess W2023752458 @default.
• W2023752458 hasPrimaryLocation W20237524581 @default.
• W2023752458 hasRelatedWork W102980731 @default.
• W2023752458 hasRelatedWork W2013475220 @default.
• W2023752458 hasRelatedWork W2387455091 @default.
• W2023752458 hasRelatedWork W2890330587 @default.
• W2023752458 hasRelatedWork W2990095507 @default.
• W2023752458 hasRelatedWork W3028445690 @default.
• W2023752458 hasRelatedWork W3029573423 @default.
• W2023752458 hasRelatedWork W4223523856 @default.
• W2023752458 hasRelatedWork W4385197877 @default.
• W2023752458 hasRelatedWork W2597201175 @default.
• W2023752458 hasVolume "14" @default.
• W2023752458 isParatext "false" @default.
• W2023752458 isRetracted "false" @default.

• next