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- W2023752761 abstract "Background and objective To compare the analgesic efficacy of tramadol alone (1.5 mg kg−1) with a tramadol (1 mg kg−1) and paracetamol combination in day-care laparoscopic patients. Methods The analgesic efficacy of intravenous tramadol alone (1.5 mg kg−1) (group T) was compared with a combination of intravenous tramadol (1 mg kg−1) and oral paracetamol 1 g (group TP) in 60 day-care laparoscopic patients in a prospective randomized double-blind clinical trial in a tertiary care hospital. Intraoperative haemodynamic responses and postoperative visual analogue scores were used to assess the analgesic efficacy. Results Only one patient (in group T) received a single dose of rescue analgesia intraoperatively. The highest pain scores were recorded at 30 min postoperatively in both groups, and rescue analgesia was needed in eight patients in group T and in 13 patients in group TP (P = 0.08). The incidence of moderate-to-severe nausea was high in group T (P = 0.001). Conclusion We conclude that reducing the dose of tramadol to 1 mg kg−1 and combining it with paracetamol 1 g orally decreased the incidence of side effects of tramadol without reducing analgesic efficacy." @default.
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- W2023752761 date "2009-06-01" @default.
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- W2023752761 title "Comparison of analgesic effect of tramadol alone and a combination of tramadol and paracetamol in day-care laparoscopic surgery" @default.
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- W2023752761 doi "https://doi.org/10.1097/eja.0b013e328324b747" @default.
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