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- W2023753890 abstract "Using ultrasonic techniques the phenomenon of mittelschmerz (midcycle lower abdominal pain) was investigated as part of a study of the periovulatory period. 96 women were studied all of whom had regular ovulatory menstrual cycles. Blood was drawn from the midfollicular phase of cycle (Day 9-11) on to determine luteinizing hormone (LH) levels. Women were questioned as to symptoms and the diameter of the developing follicle was measured in 3 planes by ultrasonograph until rupture. 34 women (35%) noticed lower abdominal pain lasting from 6-12 hours during midcycle. In 27 the discomfort was localized to one or the other iliac fossa which in all but 2 cases corresponded to the side of the developing follicle. In 7 patients the pain was central and suprapubic. 77% of patients felt pain on the day of peak plasma LH. When data were analyzed in relation to the ultrasonically determined time of ovulation it was found that in 31 of the 34 (91%) the pain had occurred in the previous 24-48 hours. The mean follicular diameter on the day of pain was 19.3 +or- 2.2 mm. Ovulation was confirmed in every cycle by a midluteal 24-hour urinary pregnanediol content of greater than 2 mg and 4 of the cycles were conceptual. Pain did not last longer than 24 hours in any subject and no analgesia was required. The recognition of mittelschmerz as a preovulatory event has application in natural family planning timing of coitus and artificial insemination." @default.
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- W2023753890 date "1980-04-05" @default.
- W2023753890 modified "2023-10-17" @default.
- W2023753890 title "Mittelschmerz is a preovulatory symptom." @default.
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- W2023753890 doi "https://doi.org/10.1136/bmj.280.6219.986" @default.
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