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- W2023759546 abstract "In this work the evaluation of the dissolution profile of captopril-hydrochlorothiazide and zidovudine-lamivudine associations were carried out by multivariate spectroscopic method. The models were developed by partial least square regression from 20 synthetic mixtures using mean-centered spectral data. The external validation was accomplished with 5 synthetic mixtures shown mean prevision error of about 1%. Good agreement was observed in the analyses of commercial drugs (content uniformity and dissolution profile), considering the results obtained by the standard chromatographic method, with prevision error lower than 10%." @default.
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- W2023759546 date "2011-09-01" @default.
- W2023759546 modified "2023-10-17" @default.
- W2023759546 title "Avaliação do perfil de dissolução de medicamentos utilizando-se espectroscopia eletrônica multivariada" @default.
- W2023759546 doi "https://doi.org/10.1590/s0100-40422011000900017" @default.
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