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- W2023761380 abstract "Rising levels of resistance amongst the major respiratory pathogens have compromised empiric antimicrobial therapy. This, coupled with a recent lack in availability of novel classes of antibacterials, has led to a need for new approaches to combat community respiratory tract infections. Bacteriological and clinical efficacy in two trials involving patients with acute bacterial sinusitis and six trials of patients with community-acquired pneumonia has shown that the development of a pharmacokinetically enhanced formulation of amoxicillin/clavulanate (Augmentin SR, available as Augmentin XR in the USA) has allowed amoxicillin/clavulanate to retain its place in the treatment of respiratory tract infections today." @default.
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- W2023761380 date "2007-12-01" @default.
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- W2023761380 title "The development of pharmacokinetically enhanced amoxicillin/clavulanate for the management of respiratory tract infections in adults" @default.
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- W2023761380 doi "https://doi.org/10.1016/j.ijantimicag.2007.07.038" @default.
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