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• W2023763412 abstract "C57BL/6 mice infected with a mixture of murine leukemia viruses (MuLV) develop a syndrome characterized by lymphoproliferation and profound immunodeficiency. Analyses of this viral mixture (LP-BM5 MuLV) showed that it includes replication-competent ecotropic and mink cell focus-inducing MuLV and defective viruses with genome sizes of 3.8-6.5 kilobases. The ecotropic and mink cell focus-inducing MuLV biologically cloned from the mixture did not induce disease, whereas viral preparations containing the ecotropic MuLV and 4.8-kilobase defective virus were active. Cells producing the 4.8-kilobase defective virus expressed an unusual gag-encoded polyprotein of Mr 60,000." @default.
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• W2023763412 date "1989-05-01" @default.
• W2023763412 modified "2023-10-12" @default.
• W2023763412 title "Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome." @default.
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• W2023763412 doi "https://doi.org/10.1073/pnas.86.10.3862" @default.
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