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- W2023770047 abstract "Neurofibromatosis 1 is one of the most common genetic diseases in humans, presenting with multiple neurofibromas and an increased risk of various benign and malignant tumors, including breast cancer.In this paper we report a case of a woman with neurofibromatosis 1 and the challenge associated with detecting an advanced breast cancer because of numerous skin neurofibromas, which were responsible for a substantial delay in cancer diagnosis. Literature concerning the association of neurofibromatosis 1 and breast cancer is reviewed and discussed.Best practice guidelines for breast cancer detection are not sufficient for the screening of neurofibromatosis 1 carriers. A more intensive clinical and imaging approach should be used if the same early detection rate as in non-neurofibromatosis 1 women is to be achieved." @default.
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- W2023770047 date "2015-03-26" @default.
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- W2023770047 title "Breast cancer and neurofibromatosis type 1: a diagnostic challenge in patients with a high number of neurofibromas" @default.
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- W2023770047 doi "https://doi.org/10.1186/s12885-015-1215-z" @default.
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