FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023771303> ?p ?o ?g. }

• W2023771303 endingPage "2723" @default.
• W2023771303 startingPage "2708" @default.
• W2023771303 abstract "Video recordings of free behavior and responses to mechanical facial stimulation were analyzed to assess whether chronic constriction injury (CCI) to the rat's infraorbital nerve (IoN) results in behavioral alterations indicative of neuropathic pain. A unilateral CCI was produced by placing loose chromic gut ligatures around the IoN. After CCI to the IoN, rats exhibited changes in both non-evoked and evoked behavior. Behavioral changes developed in two phases. Early after CCI (postoperative days 1–15), rats showed increased face-grooming activity with face-wash strokes directed to the injured nerve territory, while the responsiveness to stimulation of this area was decreased. Later after CCI (postoperative days 15–130), the prevalence of asymmetric face grooming was reduced but remained significantly increased compared to control rats. The early hyporesponsiveness was abruptly replaced by an extreme hyperresponsiveness: all stimulus intensities applied to the injured nerve territory evoked the “maximal” response (brisk head withdrawal, avoidance behavior plus directed face grooming). This response was never observed in control rats. Concurrently, IoN ligation rats showed a limited increase in the responsiveness to stimulation of the contralateral IoN territory, and around postoperative days 30–40 the responsiveness to stimulation of facial areas outside the IoN territories also increased. The hyperresponsiveness to stimulation of the ligated IoN territory slightly decreased from 60 d postoperative. Throughout the study, IoN ligation rats showed decreased exploratory behavior, displayed more freezing-like behavior, had a slower body weight gain, and a higher defecation rate, compared to control rats. The behavioral alterations observed after CCI to the IoN are indicative of severe sensory disturbances within the territory of the injured nerve: mechanical allodynia develops after a period of relative hypo- /anesthesia during which behavioral signs of recurrent spontaneous, aversive (possibly painful) sensations (paresthesias/dysesthesias) are maximal." @default.
• W2023771303 created "2016-06-24" @default.
• W2023771303 creator A5026698386 @default.
• W2023771303 creator A5032181317 @default.
• W2023771303 creator A5048175062 @default.
• W2023771303 date "1994-05-01" @default.
• W2023771303 modified "2023-10-09" @default.
• W2023771303 title "Behavioral evidence of trigeminal neuropathic pain following chronic constriction injury to the rat's infraorbital nerve" @default.
• W2023771303 cites W1588347471 @default.
• W2023771303 cites W1591503579 @default.
• W2023771303 cites W1608794387 @default.
• W2023771303 cites W166467819 @default.
• W2023771303 cites W1764887409 @default.
• W2023771303 cites W1814882149 @default.
• W2023771303 cites W1878468192 @default.
• W2023771303 cites W1965866432 @default.
• W2023771303 cites W1967093046 @default.
• W2023771303 cites W1969566902 @default.
• W2023771303 cites W1969668074 @default.
• W2023771303 cites W1971063834 @default.
• W2023771303 cites W1974054529 @default.
• W2023771303 cites W1974758710 @default.
• W2023771303 cites W1976256963 @default.
• W2023771303 cites W1976757071 @default.
• W2023771303 cites W1977499333 @default.
• W2023771303 cites W1989024053 @default.
• W2023771303 cites W1989444021 @default.
• W2023771303 cites W1990920937 @default.
• W2023771303 cites W1991550485 @default.
• W2023771303 cites W1993303466 @default.
• W2023771303 cites W1994018514 @default.
• W2023771303 cites W1998992899 @default.
• W2023771303 cites W2001400071 @default.
• W2023771303 cites W2005440480 @default.
• W2023771303 cites W2007279008 @default.
• W2023771303 cites W2011658787 @default.
• W2023771303 cites W2012398804 @default.
• W2023771303 cites W2014305186 @default.
• W2023771303 cites W2014888537 @default.
• W2023771303 cites W2017357594 @default.
• W2023771303 cites W2021478036 @default.
• W2023771303 cites W2021639837 @default.
• W2023771303 cites W2023414643 @default.
• W2023771303 cites W2027294742 @default.
• W2023771303 cites W2027880903 @default.
• W2023771303 cites W2042120969 @default.
• W2023771303 cites W2042691485 @default.
• W2023771303 cites W2043536417 @default.
• W2023771303 cites W2045327761 @default.
• W2023771303 cites W2046369173 @default.
• W2023771303 cites W2048085376 @default.
• W2023771303 cites W2051988141 @default.
• W2023771303 cites W2052027207 @default.
• W2023771303 cites W2058020736 @default.
• W2023771303 cites W2063223361 @default.
• W2023771303 cites W2066421773 @default.
• W2023771303 cites W2067924690 @default.
• W2023771303 cites W2073236751 @default.
• W2023771303 cites W2076673607 @default.
• W2023771303 cites W2076738174 @default.
• W2023771303 cites W2078411537 @default.
• W2023771303 cites W2082904249 @default.
• W2023771303 cites W2085938341 @default.
• W2023771303 cites W2092003861 @default.
• W2023771303 cites W2093217600 @default.
• W2023771303 cites W2093895073 @default.
• W2023771303 cites W2097796725 @default.
• W2023771303 cites W2103108594 @default.
• W2023771303 cites W2117566081 @default.
• W2023771303 cites W2119543677 @default.
• W2023771303 cites W2121518535 @default.
• W2023771303 cites W2140910583 @default.
• W2023771303 cites W2143141394 @default.
• W2023771303 cites W2145973505 @default.
• W2023771303 cites W2150627463 @default.
• W2023771303 cites W2162304282 @default.
• W2023771303 cites W2163329495 @default.
• W2023771303 cites W2279876422 @default.
• W2023771303 cites W2309422288 @default.
• W2023771303 cites W2317814136 @default.
• W2023771303 cites W2321150685 @default.
• W2023771303 cites W2327001917 @default.
• W2023771303 cites W2409860536 @default.
• W2023771303 cites W591371112 @default.
• W2023771303 doi "https://doi.org/10.1523/jneurosci.14-05-02708.1994" @default.
• W2023771303 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6577477" @default.
• W2023771303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8182437" @default.
• W2023771303 hasPublicationYear "1994" @default.
• W2023771303 type Work @default.
• W2023771303 sameAs 2023771303 @default.
• W2023771303 citedByCount "485" @default.
• W2023771303 countsByYear W20237713032012 @default.
• W2023771303 countsByYear W20237713032013 @default.
• W2023771303 countsByYear W20237713032014 @default.
• W2023771303 countsByYear W20237713032015 @default.
• W2023771303 countsByYear W20237713032016 @default.
• W2023771303 countsByYear W20237713032017 @default.
• W2023771303 countsByYear W20237713032018 @default.

• next