FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023774614> ?p ?o ?g. }

• W2023774614 endingPage "271" @default.
• W2023774614 startingPage "265" @default.
• W2023774614 abstract "Posttransplantation lymphoproliferative disorder (PTLD) is a well-known complication of immunosuppression associated with solid organ transplantation. The donor or host origin of PTLD may influence the outcome of the disease as it has been reported that a donor origin may be associated with a better prognosis. The aim of the study was to determine the origin (recipient or donor) of 12 PTLD occurring in kidney transplant recipients and to correlate the results with clinical findings.Origin of PTLD was determined using HLA DRB1 molecular typing, analysis of multiple short-tandem repeat microsatellite loci, and HLA class I antigen expression by immunohistochemistry.Combining the three techniques, we found that eight cases originated from the recipient and four cases originated from the donor. The results of the three techniques were concordant and altogether assigned the origin of the tumors. All the donor-origin PTLD were strictly localized to the kidney graft, developed after a mean time of 5 months after transplantation, and regressed after reduction of immunosuppression. In contrast, seven of the eight recipient-origin PTLD presented as multisystemic disease, occurred a mean time of 75.7 months after the transplantation, and had a worse outcome (mortality, five deaths of eight patients, 62.5%).These results suggest that PTLD originating from the donor arise in the first year after transplantation into the graft, and that recipient-origin PTLD develop later as an invasive disease. Because it permits simultaneously the analysis of cell morphology and tumor origin, immunohistochemistry is a more reliable technique in the case of graft tumors associated with allograft rejection. The determination of the origin of the tumors seems to be of value in the management of PTLD to predict the outcome and to adapt therapy." @default.
• W2023774614 created "2016-06-24" @default.
• W2023774614 creator A5006187873 @default.
• W2023774614 creator A5013842512 @default.
• W2023774614 creator A5020630930 @default.
• W2023774614 creator A5026625329 @default.
• W2023774614 creator A5037664471 @default.
• W2023774614 creator A5042467771 @default.
• W2023774614 creator A5053031492 @default.
• W2023774614 creator A5062958415 @default.
• W2023774614 date "2002-01-01" @default.
• W2023774614 modified "2023-10-11" @default.
• W2023774614 title "INFLUENCE OF HOST-RECIPIENT ORIGIN ON CLINICAL ASPECTS OF POSTTRANSPLANTATION LYMPHOPROLIFERATIVE DISORDERS IN KIDNEY TRANSPLANTATION" @default.
• W2023774614 cites W1546795188 @default.
• W2023774614 cites W1874138720 @default.
• W2023774614 cites W1968280028 @default.
• W2023774614 cites W1976179643 @default.
• W2023774614 cites W1991955609 @default.
• W2023774614 cites W1999983131 @default.
• W2023774614 cites W2004867952 @default.
• W2023774614 cites W2008323503 @default.
• W2023774614 cites W2026689623 @default.
• W2023774614 cites W2044155770 @default.
• W2023774614 cites W2057082219 @default.
• W2023774614 cites W2074325884 @default.
• W2023774614 cites W2075300305 @default.
• W2023774614 cites W2108241853 @default.
• W2023774614 cites W2118094114 @default.
• W2023774614 cites W2124314287 @default.
• W2023774614 cites W2131598459 @default.
• W2023774614 cites W2133874072 @default.
• W2023774614 cites W2165903418 @default.
• W2023774614 cites W2255013549 @default.
• W2023774614 cites W2333917354 @default.
• W2023774614 cites W2334858305 @default.
• W2023774614 cites W2341259055 @default.
• W2023774614 cites W4237689352 @default.
• W2023774614 cites W4253113947 @default.
• W2023774614 cites W61415573 @default.
• W2023774614 doi "https://doi.org/10.1097/00007890-200201270-00020" @default.
• W2023774614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11821742" @default.
• W2023774614 hasPublicationYear "2002" @default.
• W2023774614 type Work @default.
• W2023774614 sameAs 2023774614 @default.
• W2023774614 citedByCount "47" @default.
• W2023774614 countsByYear W20237746142012 @default.
• W2023774614 countsByYear W20237746142013 @default.
• W2023774614 countsByYear W20237746142014 @default.
• W2023774614 countsByYear W20237746142015 @default.
• W2023774614 countsByYear W20237746142016 @default.
• W2023774614 countsByYear W20237746142017 @default.
• W2023774614 countsByYear W20237746142018 @default.
• W2023774614 countsByYear W20237746142019 @default.
• W2023774614 countsByYear W20237746142020 @default.
• W2023774614 countsByYear W20237746142021 @default.
• W2023774614 countsByYear W20237746142022 @default.
• W2023774614 crossrefType "journal-article" @default.
• W2023774614 hasAuthorship W2023774614A5006187873 @default.
• W2023774614 hasAuthorship W2023774614A5013842512 @default.
• W2023774614 hasAuthorship W2023774614A5020630930 @default.
• W2023774614 hasAuthorship W2023774614A5026625329 @default.
• W2023774614 hasAuthorship W2023774614A5037664471 @default.
• W2023774614 hasAuthorship W2023774614A5042467771 @default.
• W2023774614 hasAuthorship W2023774614A5053031492 @default.
• W2023774614 hasAuthorship W2023774614A5062958415 @default.
• W2023774614 hasBestOaLocation W20237746141 @default.
• W2023774614 hasConcept C126322002 @default.
• W2023774614 hasConcept C142724271 @default.
• W2023774614 hasConcept C147483822 @default.
• W2023774614 hasConcept C168444539 @default.
• W2023774614 hasConcept C188280979 @default.
• W2023774614 hasConcept C203014093 @default.
• W2023774614 hasConcept C2522874641 @default.
• W2023774614 hasConcept C2776995267 @default.
• W2023774614 hasConcept C2779338263 @default.
• W2023774614 hasConcept C2780091579 @default.
• W2023774614 hasConcept C2780252810 @default.
• W2023774614 hasConcept C2780303639 @default.
• W2023774614 hasConcept C2781146716 @default.
• W2023774614 hasConcept C2781375147 @default.
• W2023774614 hasConcept C2911091166 @default.
• W2023774614 hasConcept C71924100 @default.
• W2023774614 hasConceptScore W2023774614C126322002 @default.
• W2023774614 hasConceptScore W2023774614C142724271 @default.
• W2023774614 hasConceptScore W2023774614C147483822 @default.
• W2023774614 hasConceptScore W2023774614C168444539 @default.
• W2023774614 hasConceptScore W2023774614C188280979 @default.
• W2023774614 hasConceptScore W2023774614C203014093 @default.
• W2023774614 hasConceptScore W2023774614C2522874641 @default.
• W2023774614 hasConceptScore W2023774614C2776995267 @default.
• W2023774614 hasConceptScore W2023774614C2779338263 @default.
• W2023774614 hasConceptScore W2023774614C2780091579 @default.
• W2023774614 hasConceptScore W2023774614C2780252810 @default.
• W2023774614 hasConceptScore W2023774614C2780303639 @default.
• W2023774614 hasConceptScore W2023774614C2781146716 @default.
• W2023774614 hasConceptScore W2023774614C2781375147 @default.
• W2023774614 hasConceptScore W2023774614C2911091166 @default.
• W2023774614 hasConceptScore W2023774614C71924100 @default.

• next