FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023774682> ?p ?o ?g. }

• W2023774682 endingPage "180" @default.
• W2023774682 startingPage "172" @default.
• W2023774682 abstract "This study examined the role of cannabinoid CB1 receptors (CB1r) in aggressive behavior. Social encounters took place in grouped and isolated mice lacking CB1r (CB1KO) and in wild-type (WT) littermates. Cognitive impulsivity was evaluated in the delayed reinforcement task (DRT). Gene expression analyses of monoaminooxidase-A (MAO-A), catechol-o-methyl-transferase (COMT), 5-hydroxytriptamine transporter (5-HTT) and 5-HT1B serotonergic receptor (5HT1Br) in the median and dorsal raphe nuclei (MnR and DR, respectively) and in the amygdala (AMY) were performed by real time-PCR. Double immunohistochemistry studies evaluated COMT and CB1r co-localization in the raphe nuclei and in the cortical (ACo), basomedian (BMA) and basolateral (BLA) amygdaloid nuclei. The behavioral effects of the CB1r agonist ACEA (1 and 2 mg/kg) on aggression were also evaluated in isolated OF1 mice. CB1KO mice housed in groups showed higher levels of offensive aggression. Isolation increased aggressive behavior only in WT. In grouped CB1KO mice COMT gene expression was significantly higher in the MnR and DR, while MAO-A gene expression was lower in the MnR. Gene expression of 5HT1Br, COMT and MAO-A was higher in the amygdala of CB1KO mice. CB1r double-immunohistochemistry revealed cytoplasmic-labeled COMT-ir cells in the raphe nuclei and in the ACo, BMA and BLA. CB1r immunolabeling was observed only in ACo, BMA and BLA, where it was localized in axons and buttons. The density of labeled processes increased in BLA. Acute administration of the CB1 agonist ACEA (2 mg/kg) significantly decreased the aggression levels of OF1 mice. These results suggest that CB1r plays an important role in social interaction and aggressive behavior." @default.
• W2023774682 created "2016-06-24" @default.
• W2023774682 creator A5004097414 @default.
• W2023774682 creator A5020787270 @default.
• W2023774682 creator A5038192955 @default.
• W2023774682 creator A5066933181 @default.
• W2023774682 creator A5071035368 @default.
• W2023774682 creator A5072251228 @default.
• W2023774682 creator A5073532676 @default.
• W2023774682 creator A5088955793 @default.
• W2023774682 date "2013-12-01" @default.
• W2023774682 modified "2023-10-18" @default.
• W2023774682 title "CB1 cannabinoid receptor-mediated aggressive behavior" @default.
• W2023774682 cites W1492266111 @default.
• W2023774682 cites W1762648457 @default.
• W2023774682 cites W1883407976 @default.
• W2023774682 cites W1964464930 @default.
• W2023774682 cites W1965588909 @default.
• W2023774682 cites W1976616440 @default.
• W2023774682 cites W1982291289 @default.
• W2023774682 cites W1984030600 @default.
• W2023774682 cites W1986205307 @default.
• W2023774682 cites W1989103708 @default.
• W2023774682 cites W1989675181 @default.
• W2023774682 cites W1989689950 @default.
• W2023774682 cites W1991543767 @default.
• W2023774682 cites W1994158001 @default.
• W2023774682 cites W1994816641 @default.
• W2023774682 cites W1998532089 @default.
• W2023774682 cites W2000801185 @default.
• W2023774682 cites W2004489614 @default.
• W2023774682 cites W2004732575 @default.
• W2023774682 cites W2012773663 @default.
• W2023774682 cites W2017089625 @default.
• W2023774682 cites W2017346439 @default.
• W2023774682 cites W2026927232 @default.
• W2023774682 cites W2027118885 @default.
• W2023774682 cites W2027352187 @default.
• W2023774682 cites W2029181309 @default.
• W2023774682 cites W2030901273 @default.
• W2023774682 cites W2031501939 @default.
• W2023774682 cites W2035089291 @default.
• W2023774682 cites W2036141226 @default.
• W2023774682 cites W2037778343 @default.
• W2023774682 cites W2039330485 @default.
• W2023774682 cites W2043588596 @default.
• W2023774682 cites W2046272916 @default.
• W2023774682 cites W2054653962 @default.
• W2023774682 cites W2059567546 @default.
• W2023774682 cites W2067577663 @default.
• W2023774682 cites W2079144291 @default.
• W2023774682 cites W2087856744 @default.
• W2023774682 cites W2090912155 @default.
• W2023774682 cites W2097747770 @default.
• W2023774682 cites W2106328570 @default.
• W2023774682 cites W2118091961 @default.
• W2023774682 cites W2123325948 @default.
• W2023774682 cites W2130587723 @default.
• W2023774682 cites W2136307385 @default.
• W2023774682 cites W2148625659 @default.
• W2023774682 cites W2149183149 @default.
• W2023774682 cites W2150821313 @default.
• W2023774682 cites W2153392906 @default.
• W2023774682 cites W2158046191 @default.
• W2023774682 cites W2160485854 @default.
• W2023774682 cites W2168201535 @default.
• W2023774682 cites W2171584675 @default.
• W2023774682 cites W76463107 @default.
• W2023774682 cites W765128932 @default.
• W2023774682 doi "https://doi.org/10.1016/j.neuropharm.2013.07.013" @default.
• W2023774682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23916480" @default.
• W2023774682 hasPublicationYear "2013" @default.
• W2023774682 type Work @default.
• W2023774682 sameAs 2023774682 @default.
• W2023774682 citedByCount "51" @default.
• W2023774682 countsByYear W20237746822014 @default.
• W2023774682 countsByYear W20237746822015 @default.
• W2023774682 countsByYear W20237746822016 @default.
• W2023774682 countsByYear W20237746822017 @default.
• W2023774682 countsByYear W20237746822018 @default.
• W2023774682 countsByYear W20237746822019 @default.
• W2023774682 countsByYear W20237746822020 @default.
• W2023774682 countsByYear W20237746822021 @default.
• W2023774682 countsByYear W20237746822022 @default.
• W2023774682 countsByYear W20237746822023 @default.
• W2023774682 crossrefType "journal-article" @default.
• W2023774682 hasAuthorship W2023774682A5004097414 @default.
• W2023774682 hasAuthorship W2023774682A5020787270 @default.
• W2023774682 hasAuthorship W2023774682A5038192955 @default.
• W2023774682 hasAuthorship W2023774682A5066933181 @default.
• W2023774682 hasAuthorship W2023774682A5071035368 @default.
• W2023774682 hasAuthorship W2023774682A5072251228 @default.
• W2023774682 hasAuthorship W2023774682A5073532676 @default.
• W2023774682 hasAuthorship W2023774682A5088955793 @default.
• W2023774682 hasConcept C126322002 @default.
• W2023774682 hasConcept C134018914 @default.
• W2023774682 hasConcept C148001335 @default.
• W2023774682 hasConcept C15744967 @default.

• next