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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023779448> ?p ?o ?g. }

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• W2023779448 abstract "Virtual screening efforts have identified several novel HDAC6 inhibitors with cellular isoform selectivity. In particular, a carbamate-protected hydroxamic acid exhibited improved effects with respect to protein hyperacetylation compared with the parent hydroxamate, possibly because of improved cell permeability. The carbamate structure therefore represents a potential prodrug concept for hydroxamic acid-containing HDAC inhibitors." @default.
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• W2023779448 date "2011-03-17" @default.
• W2023779448 modified "2023-10-18" @default.
• W2023779448 title "Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors" @default.
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• W2023779448 doi "https://doi.org/10.1002/cmdc.201100007" @default.
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