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- W2023782592 abstract "The distribution of 1-methyl-14C caffeine and metabolites in brain and liver subcellular fractions, at various time intervals after i.p. injection, has been studied in the rat. Caffeine penetrates rapidly in intracellular compartments of tissues and accumulates in the cytoplasm. Caffeine and metabolites do not tend to accumulate in sealed cytoplasmic compartments, except in the nuclear fraction. The different distribution of caffeine and metabolites in brain and liver subcellular fractions suggests a more active formation or accumulation of metabolites in liver particulate fractions in respect of brain." @default.
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- W2023782592 title "Distribution of caffeine and metabolites in brain and liver subcellular fractions in the rat" @default.
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- W2023782592 doi "https://doi.org/10.1016/s0031-6989(75)80016-6" @default.
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