FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023788128> ?p ?o ?g. }

• W2023788128 endingPage "993" @default.
• W2023788128 startingPage "981" @default.
• W2023788128 abstract "Limb girdle muscular dystrophy type 2B form (LGMD‐2B) and Miyoshi myopathy (MM) are both caused by mutations in the dysferlin (dysf) gene. In this study, we used dysferlin‐deficient sjl mice as a mouse model to study cell therapy for LGMD‐2B and MM. A single‐blind study evaluated the therapeutic potential of human umbilical cord blood (HUCB) as a source of myogenic progenitor stem cells. Three groups of donor cells were used: unfractionated mononuclear HUCB cells, HUCB subfractionated to enrich for cells that were negative for lineage surface markers (LIN−) and substantially enriched for the CD34 surface marker (CD34+), and irradiated control spleen cells. We administrated 1 × 106 donor cells to each animal intravenously and euthanized them at different time points (1–12 weeks) after transplantation. All animals were immunosuppressed (FK506 and leflunomide) from the day before the injection until the time of euthanasia. Immunohistochemical analyses documented that a small number of human cells from the whole HUCB and LIN−CD34+/−‐enriched HUCB subgroups engraft in the recipient muscle to express both dysferlin and human‐specific dystrophin at 12 weeks after transplantation. We conclude that myogenic progenitor cells are present in the HUCB, that they can disseminate into muscle after intravenous administration, and that they are capable of myogenic differentiation in host muscle." @default.
• W2023788128 created "2016-06-24" @default.
• W2023788128 creator A5013481889 @default.
• W2023788128 creator A5025571618 @default.
• W2023788128 creator A5055718219 @default.
• W2023788128 creator A5060859659 @default.
• W2023788128 creator A5080998433 @default.
• W2023788128 date "2004-11-01" @default.
• W2023788128 modified "2023-09-23" @default.
• W2023788128 title "Human Umbilical Cord Blood Cells Differentiate into Muscle in <i>sjl</i> Muscular Dystrophy Mice" @default.
• W2023788128 cites W1551910894 @default.
• W2023788128 cites W1772894161 @default.
• W2023788128 cites W1970561503 @default.
• W2023788128 cites W1973278012 @default.
• W2023788128 cites W1983259364 @default.
• W2023788128 cites W1989378631 @default.
• W2023788128 cites W1991248271 @default.
• W2023788128 cites W1991374176 @default.
• W2023788128 cites W1994971898 @default.
• W2023788128 cites W2004484191 @default.
• W2023788128 cites W2013621644 @default.
• W2023788128 cites W2016823790 @default.
• W2023788128 cites W2018303730 @default.
• W2023788128 cites W2021440286 @default.
• W2023788128 cites W2034273480 @default.
• W2023788128 cites W2037971514 @default.
• W2023788128 cites W2043317882 @default.
• W2023788128 cites W2048441156 @default.
• W2023788128 cites W2062867597 @default.
• W2023788128 cites W2069209063 @default.
• W2023788128 cites W2076462595 @default.
• W2023788128 cites W2084936584 @default.
• W2023788128 cites W2087990357 @default.
• W2023788128 cites W2089154676 @default.
• W2023788128 cites W2109794889 @default.
• W2023788128 cites W2112574432 @default.
• W2023788128 cites W2113561239 @default.
• W2023788128 cites W2124791711 @default.
• W2023788128 cites W2127340198 @default.
• W2023788128 cites W2130513320 @default.
• W2023788128 cites W2134003298 @default.
• W2023788128 cites W2137956382 @default.
• W2023788128 cites W2144116778 @default.
• W2023788128 cites W2169334227 @default.
• W2023788128 cites W2243479910 @default.
• W2023788128 cites W2330713242 @default.
• W2023788128 cites W2415441481 @default.
• W2023788128 cites W2417007885 @default.
• W2023788128 cites W4323053893 @default.
• W2023788128 cites W58217582 @default.
• W2023788128 cites W63648609 @default.
• W2023788128 doi "https://doi.org/10.1634/stemcells.22-6-981" @default.
• W2023788128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15536189" @default.
• W2023788128 hasPublicationYear "2004" @default.
• W2023788128 type Work @default.
• W2023788128 sameAs 2023788128 @default.
• W2023788128 citedByCount "45" @default.
• W2023788128 countsByYear W20237881282012 @default.
• W2023788128 countsByYear W20237881282013 @default.
• W2023788128 countsByYear W20237881282014 @default.
• W2023788128 countsByYear W20237881282016 @default.
• W2023788128 countsByYear W20237881282017 @default.
• W2023788128 countsByYear W20237881282020 @default.
• W2023788128 crossrefType "journal-article" @default.
• W2023788128 hasAuthorship W2023788128A5013481889 @default.
• W2023788128 hasAuthorship W2023788128A5025571618 @default.
• W2023788128 hasAuthorship W2023788128A5055718219 @default.
• W2023788128 hasAuthorship W2023788128A5060859659 @default.
• W2023788128 hasAuthorship W2023788128A5080998433 @default.
• W2023788128 hasBestOaLocation W20237881281 @default.
• W2023788128 hasConcept C10205521 @default.
• W2023788128 hasConcept C104317684 @default.
• W2023788128 hasConcept C126322002 @default.
• W2023788128 hasConcept C142724271 @default.
• W2023788128 hasConcept C201750760 @default.
• W2023788128 hasConcept C203014093 @default.
• W2023788128 hasConcept C207200792 @default.
• W2023788128 hasConcept C2776955114 @default.
• W2023788128 hasConcept C2778463287 @default.
• W2023788128 hasConcept C2778649560 @default.
• W2023788128 hasConcept C2779030066 @default.
• W2023788128 hasConcept C28328180 @default.
• W2023788128 hasConcept C2911091166 @default.
• W2023788128 hasConcept C37113945 @default.
• W2023788128 hasConcept C3763915 @default.
• W2023788128 hasConcept C501734568 @default.
• W2023788128 hasConcept C54355233 @default.
• W2023788128 hasConcept C71924100 @default.
• W2023788128 hasConcept C86803240 @default.
• W2023788128 hasConcept C95444343 @default.
• W2023788128 hasConcept C97816823 @default.
• W2023788128 hasConceptScore W2023788128C10205521 @default.
• W2023788128 hasConceptScore W2023788128C104317684 @default.
• W2023788128 hasConceptScore W2023788128C126322002 @default.
• W2023788128 hasConceptScore W2023788128C142724271 @default.
• W2023788128 hasConceptScore W2023788128C201750760 @default.
• W2023788128 hasConceptScore W2023788128C203014093 @default.
• W2023788128 hasConceptScore W2023788128C207200792 @default.

• next