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- W2023793444 abstract "L-745,337 [5-methanesulphonamido-6-(2,4-difluorothiophenyl)-1-indanone] a selective cyclooxygenase-2 inhibitor reversed hyperalgesia induced by carrageenan in rats without causing gastric ulceration at doses 100 times those causing antinociception. In contrast, piroxicam and indomethacin produced ulcerations at antinociceptive doses. These findings demonstrate that L-745,337 possesses antinociceptive activity but has a reduced liability for gastric ulceration." @default.
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- W2023793444 date "1994-12-01" @default.
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- W2023793444 title "L-745,337: A selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats" @default.
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- W2023793444 doi "https://doi.org/10.1016/0028-3908(94)90137-6" @default.
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