Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023807404> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2023807404 abstract "Histotripsy is a non-invasive, pulsed ultrasound technology where controlled cavitation is used to homogenize targeted tissue. We sought to assess the possibility that histotripsy may increase metastatic spread of tumor by quantifying the number of lung metastasis apparent after histotripsy treatment of aggressive renal VX-2 tumor compared to nontreated controls. VX-2 tumor was implanted in the left kidneys of 28 New Zealand White rabbits. Twenty rabbits were treated with histotripsy (day 13 after implantation) while 8 served as controls. All rabbits underwent left nephrectomy (day 14) and then were euthanized (day 19). This study was powered to detect a doubling in metastatic rate. Homogenized tumor was seen in all treated nephrectomy specimens. Whole-mount, coronal lung sections were viewed to calculate number and density of metastases. Viable tumor was present in all 28 lungs examined. Histology confirmed fractionation of tumor in all treatment rabbits. There was not a statistical difference in total lung metastases (88.7 vs. 72.5; p=0.29) or metastatic density (8.9 vs. 7.0 mets/cm2; p=0.22) between treated and control rabbits. Further investigation is planned to validate these results in the VX-2 model and to assess metastatic rates in less aggressive tumors treated with histotripsy." @default.
- W2023807404 created "2016-06-24" @default.
- W2023807404 creator A5019985228 @default.
- W2023807404 creator A5034792642 @default.
- W2023807404 creator A5046270398 @default.
- W2023807404 creator A5087439117 @default.
- W2023807404 creator A5088298096 @default.
- W2023807404 date "2012-01-01" @default.
- W2023807404 modified "2023-09-23" @default.
- W2023807404 title "Histotripsy and metastasis: Assessment in a renal VX-2 rabbit tumor model" @default.
- W2023807404 doi "https://doi.org/10.1063/1.4757363" @default.
- W2023807404 hasPublicationYear "2012" @default.
- W2023807404 type Work @default.
- W2023807404 sameAs 2023807404 @default.
- W2023807404 citedByCount "0" @default.
- W2023807404 crossrefType "proceedings-article" @default.
- W2023807404 hasAuthorship W2023807404A5019985228 @default.
- W2023807404 hasAuthorship W2023807404A5034792642 @default.
- W2023807404 hasAuthorship W2023807404A5046270398 @default.
- W2023807404 hasAuthorship W2023807404A5087439117 @default.
- W2023807404 hasAuthorship W2023807404A5088298096 @default.
- W2023807404 hasConcept C121608353 @default.
- W2023807404 hasConcept C126322002 @default.
- W2023807404 hasConcept C126838900 @default.
- W2023807404 hasConcept C126894567 @default.
- W2023807404 hasConcept C142724271 @default.
- W2023807404 hasConcept C143753070 @default.
- W2023807404 hasConcept C2777714996 @default.
- W2023807404 hasConcept C2779013556 @default.
- W2023807404 hasConcept C2780091579 @default.
- W2023807404 hasConcept C2780227381 @default.
- W2023807404 hasConcept C2780283643 @default.
- W2023807404 hasConcept C2989005 @default.
- W2023807404 hasConcept C57742111 @default.
- W2023807404 hasConcept C71924100 @default.
- W2023807404 hasConceptScore W2023807404C121608353 @default.
- W2023807404 hasConceptScore W2023807404C126322002 @default.
- W2023807404 hasConceptScore W2023807404C126838900 @default.
- W2023807404 hasConceptScore W2023807404C126894567 @default.
- W2023807404 hasConceptScore W2023807404C142724271 @default.
- W2023807404 hasConceptScore W2023807404C143753070 @default.
- W2023807404 hasConceptScore W2023807404C2777714996 @default.
- W2023807404 hasConceptScore W2023807404C2779013556 @default.
- W2023807404 hasConceptScore W2023807404C2780091579 @default.
- W2023807404 hasConceptScore W2023807404C2780227381 @default.
- W2023807404 hasConceptScore W2023807404C2780283643 @default.
- W2023807404 hasConceptScore W2023807404C2989005 @default.
- W2023807404 hasConceptScore W2023807404C57742111 @default.
- W2023807404 hasConceptScore W2023807404C71924100 @default.
- W2023807404 hasLocation W20238074041 @default.
- W2023807404 hasOpenAccess W2023807404 @default.
- W2023807404 hasPrimaryLocation W20238074041 @default.
- W2023807404 hasRelatedWork W1882516778 @default.
- W2023807404 hasRelatedWork W1992965120 @default.
- W2023807404 hasRelatedWork W1999434280 @default.
- W2023807404 hasRelatedWork W2002262255 @default.
- W2023807404 hasRelatedWork W2027256805 @default.
- W2023807404 hasRelatedWork W2067266504 @default.
- W2023807404 hasRelatedWork W2406092126 @default.
- W2023807404 hasRelatedWork W2730590599 @default.
- W2023807404 hasRelatedWork W3111892599 @default.
- W2023807404 hasRelatedWork W4210572810 @default.
- W2023807404 isParatext "false" @default.
- W2023807404 isRetracted "false" @default.
- W2023807404 magId "2023807404" @default.
- W2023807404 workType "article" @default.